SCX and MYF5

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		SCX	MYF5
Description		scleraxis bHLH transcription factor	myogenic factor 5
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Transcription Regulator Complex	Chromatin Nucleoplasm RNA Polymerase II Transcription Regulator Complex
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Protein Binding BHLH Transcription Factor Binding Sequence-specific DNA Binding Protein Dimerization Activity E-box Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Protein Dimerization Activity E-box Binding
	Biological Process	Mesoderm Formation Tissue Homeostasis Endochondral Ossification Chondrocyte Differentiation Heart Valve Morphogenesis Heart Valve Formation Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Cell Population Proliferation Positive Regulation Of Gene Expression Cell Differentiation Collagen Fibril Organization BMP Signaling Pathway Developmental Process Positive Regulation Of Collagen Biosynthetic Process Skeletal Muscle Cell Differentiation Tendon Development Tendon Cell Differentiation Tendon Formation Deltoid Tuberosity Development Negative Regulation Of Apoptotic Process Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Embryonic Skeletal System Development Sertoli Cell Differentiation Face Morphogenesis Regulation Of Cartilage Development Positive Regulation Of Cartilage Development Sclerotome Development Cellular Response To Mechanical Stimulus Cellular Response To Transforming Growth Factor Beta Stimulus Positive Regulation Of Gastrulation	Cartilage Condensation Ossification Somitogenesis Regulation Of Cell-matrix Adhesion Regulation Of Transcription By RNA Polymerase II Muscle Organ Development Skeletal Muscle Tissue Development Extracellular Matrix Organization Skeletal Muscle Cell Differentiation Muscle Cell Fate Commitment Camera-type Eye Development Positive Regulation Of Myoblast Differentiation Positive Regulation Of Transcription By RNA Polymerase II Embryonic Skeletal System Morphogenesis Positive Regulation Of Skeletal Muscle Fiber Development Muscle Tissue Morphogenesis
Pathways			Myogenesis Myogenesis
Drugs
Diseases
GWAS
Interacting Genes		4 interacting genes: MYF5 NCK2 TCF3 TCF4	34 interacting genes: ANKRD11 AQP1 C14orf119 CALM1 CALM2 CALM3 CCDC13 CHIC2 CSNK2A1 CSNK2A2 ENKD1 FAM124B FIGLA ID1 ID2 ID3 ITGB4 MDFI MSGN1 NHLH2 PACRGL PIN1 RARG SCX SGF29 SNAPC5 TCEANC TCF3 TLE5 ZNF250 ZNF417 ZNF575 ZNF587 ZNF835
Entrez ID		642658	4617
HPRD ID		19332	01168
Ensembl ID		ENSG00000260428	ENSG00000111049
Uniprot IDs		Q7RTU7	P13349
PDB IDs
Enriched GO Terms of Interacting Partners?
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