SRSF1 and SRSF5

Number of citations of the paper that reports this interaction (PubMedID 9799243)
82

Data Source:
BioGRID (pull down)

		SRSF1	SRSF5
Description		serine and arginine rich splicing factor 1	serine and arginine rich splicing factor 5
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Nuclear Speck Catalytic Step 2 Spliceosome	Nucleoplasm Nucleolus Cytosol Nuclear Speck
	Molecular Function	RNA Binding MRNA Binding Protein Binding Protein Kinase B Binding DNA Topoisomerase Binding	RNA Binding MRNA Binding Protein Binding Protein Kinase B Binding
	Biological Process	Alternative MRNA Splicing, Via Spliceosome MRNA 5'-splice Site Recognition MRNA Splicing, Via Spliceosome MRNA Splice Site Selection MRNA Processing Positive Regulation Of RNA Splicing Oligodendrocyte Differentiation MRNA Transport Liver Regeneration	MRNA Splicing, Via Spliceosome MRNA Splice Site Selection MRNA Processing Cellular Response To Insulin Stimulus Positive Regulation Of RNA Splicing Regulation Of Cell Cycle Liver Regeneration
Pathways		Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination	Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination
Drugs		Copper
Diseases
GWAS		Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223)	Mean spheric corpuscular volume ( 32888494) Red blood cell count ( 32888494)
Interacting Genes		42 interacting genes: AKAP17A APP BCL10 C1QBP CACNA1A CD8A CDC42 CDK12 CDK6 CLK1 DANCR DIDO1 DYRK1A GEMIN2 HIPK3 HNRNPA0 LNX1 LUC7L3 NFYA NXF1 PPARG PRPF4 PRPF4B PSIP1 RNPS1 SCAF11 SNRNP70 SREK1 SRPK1 SRPK2 SRSF10 SRSF11 SRSF5 TCERG1 TNPO3 TOP1 TP53 U2AF1 U2AF2 XBP1 YTHDC1 ZRSR2	20 interacting genes: CALM1 CCR2 CD101 CLK1 DYRK1A HIPK3 MAPK14 MAPK6 OLFM2 PPARGC1A RPS6KA1 SMURF1 SNRPF SREK1 SRPK1 SRPK2 SRSF1 TIAM1 TNK2 ZRSR2
Entrez ID		6426	6430
HPRD ID		02887	02948
Ensembl ID		ENSG00000136450	ENSG00000100650
Uniprot IDs		Q07955 Q59FA2	A0A024R6D8 Q13243 Q86U32
PDB IDs		1X4A 2M7S 2M8D 2O3D 3BEG 4C0O 6HPJ 7ABG
Enriched GO Terms of Interacting Partners?
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