SMOC1 and SYNJ2BP

		SMOC1	SYNJ2BP
Description		SPARC related modular calcium binding 1	synaptojanin 2 binding protein
Image		No pdb structure
GO Annotations	Cellular Component	Basement Membrane Extracellular Space	Mitochondrion Basolateral Plasma Membrane Cell Junction Integral Component Of Mitochondrial Outer Membrane Neuromuscular Junction Neuron Projection Postsynaptic Density Membrane
	Molecular Function	Calcium Ion Binding Protein Binding Heparin Binding Extracellular Matrix Binding	Protein Binding
	Biological Process	Eye Development Cell Differentiation Extracellular Matrix Organization Regulation Of Osteoblast Differentiation Limb Development	Negative Regulation Of Endothelial Cell Proliferation Chemical Synaptic Transmission Regulation Of Notch Signaling Pathway Embryo Development Negative Regulation Of Endothelial Cell Migration Negative Regulation Of Angiogenesis Receptor Clustering Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Negative Regulation Of ERK1 And ERK2 Cascade Receptor Localization To Synapse Cell-cell Adhesion Negative Regulation Of Sprouting Angiogenesis
Pathways
Drugs
Diseases
GWAS		Blood protein levels ( 30072576 29875488) Bone mineral density ( 24249740) Daytime sleep phenotypes ( 27126917) Digit length ratio ( 29659830) Digit length ratio (left hand) ( 29659830) Digit length ratio (right hand) ( 29659830) Heel bone mineral density ( 30598549) Mean corpuscular hemoglobin ( 32888494 27863252) Mean corpuscular volume ( 32888494) Peginterferon alfa-2a treatment response in chronic hepatitis B infection ( 30972912) Peripheral artery disease ( 31285632) Red blood cell traits ( 23222517) Red cell distribution width ( 32888494 27863252) Refractive error ( 32231278) Triglyceride levels ( 30108155) Tuberculosis ( 24057671)	Blood pressure ( 24954895) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) LDL cholesterol ( 30275531) Motor coordination ( 34177493) Normal facial asymmetry (angle of surface orientation score) ( 30631343)
Interacting Genes		12 interacting genes: COX16 CYSRT1 KRTAP1-1 KRTAP10-3 KRTAP10-8 NOTCH2NLA NR4A3 SYNJ2BP TCF4 TNC TTC9 VGLL3	34 interacting genes: ACTB ACVR2A ACVR2B APP AQP6 CD79A CPLX4 CREB3L1 CYB561 EBP ELOVL5 ELOVL7 ERGIC3 FAM210B FCER1G LHFPL5 LRP1 LRP2 LRP8 MEDAG RALBP1 REEP4 RPS6KA1 SLC10A6 SLC7A8 SMOC1 SYNJ2 THEM5 TLCD4 TMEM101 TMEM14B TMEM242 UBQLN1 USHBP1
Entrez ID		64093	55333
HPRD ID		12244	15455
Ensembl ID		ENSG00000198732	ENSG00000213463
Uniprot IDs		A0A024R6E0 Q9H4F8	A0A024R670 P57105
PDB IDs			2ENO 2JIK 2JIN
Enriched GO Terms of Interacting Partners?
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