GALNT11 and MUC4

Number of citations of the paper that reports this interaction (PubMedID 11925450)
56

Data Source:
HPRD (in vitro)

		GALNT11	MUC4
Description		polypeptide N-acetylgalactosaminyltransferase 11	mucin 4, cell surface associated
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Golgi Apparatus Integral Component Of Membrane	Extracellular Space Golgi Lumen Plasma Membrane Integral Component Of Plasma Membrane Membrane Extracellular Matrix Vesicle Extracellular Exosome
	Molecular Function	Polypeptide N-acetylgalactosaminyltransferase Activity Notch Binding Carbohydrate Binding Metal Ion Binding	ErbB-2 Class Receptor Binding Extracellular Matrix Constituent, Lubricant Activity
	Biological Process	Notch Receptor Processing Determination Of Left/right Symmetry Regulation Of Notch Signaling Pathway O-glycan Processing Protein O-linked Glycosylation Via Threonine Cilium Assembly Notch Signaling Involved In Heart Development	Cell-matrix Adhesion Regulation Of Signaling Receptor Activity Maintenance Of Gastrointestinal Epithelium
Pathways		O-linked glycosylation of mucins	Defective GALNT3 causes familial hyperphosphatemic tumoral calcinosis (HFTC) Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS) Defective GALNT12 causes colorectal cancer 1 (CRCS1) Dectin-2 family O-linked glycosylation of mucins Termination of O-glycan biosynthesis
Drugs
Diseases
GWAS		Kidney function decline traits ( 25493955) Post bronchodilator FEV1/FVC ratio ( 26634245)	Estimated glomerular filtration rate ( 31015462) Lung disease severity in cystic fibrosis ( 26417704) Red blood cell density in sickle cell anemia ( 28552477)
Interacting Genes		3 interacting genes: GSC2 MUC4 SGTB	5 interacting genes: EGFR ERBB2 ERBB3 ERBB4 GALNT11
Entrez ID		63917	4585
HPRD ID		13560	11829
Ensembl ID		ENSG00000178234	ENSG00000145113
Uniprot IDs		A0A090N7X6 B7Z5G5 Q8NCW6	A0A0G2JS65 A0T3F4 E9PDY6 Q99102
PDB IDs
Enriched GO Terms of Interacting Partners?
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