UBE2O and RNF10

Number of citations of the paper that reports this interaction (PubMedID 19549727)
74

Data Source:
BioGRID (two hybrid)

		UBE2O	RNF10
Description		ubiquitin conjugating enzyme E2 O	ring finger protein 10
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Nuclear Body	Nucleus Cytoplasm
	Molecular Function	RNA Binding Ubiquitin-protein Transferase Activity Cysteine-type Endopeptidase Inhibitor Activity Protein Binding ATP Binding Ubiquitin Protein Ligase Activity Ubiquitin Conjugating Enzyme Activity	Transcription Cis-regulatory Region Binding Protein Binding Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Protein Monoubiquitination Negative Regulation Of Endopeptidase Activity Positive Regulation Of BMP Signaling Pathway Retrograde Transport, Endosome To Golgi Negative Regulation Of Apoptotic Process Protein K63-linked Ubiquitination	Negative Regulation Of Schwann Cell Proliferation Positive Regulation Of Myelination Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Protein Autoubiquitination
Pathways		Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		High light scatter reticulocyte percentage of red cells ( 32888494) Lymphocyte counts ( 27863252) Lymphocyte percentage of white cells ( 32888494 27863252) Mitochondrial DNA levels ( 25240745) Neutrophil percentage of white cells ( 32888494) Platelet distribution width ( 32888494) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494) White blood cell count ( 32888494)	Chronotype ( 26955885) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Red cell distribution width ( 32888494) Reticulocyte fraction of red cells ( 27863252) Sensorimotor dexterity ( 31596458) Type 1 diabetes nephropathy ( 23028342)
Interacting Genes		18 interacting genes: APPL1 BAP1 CPNE1 CPNE2 CPNE4 HEXIM1 ITCH MAF MDM2 MXI1 PRKN RNF10 RNF31 SFMBT2 SHBG TRIM27 UBC UBE2D3	32 interacting genes: CCDC122 CCDC90B COL4A5 DYSF EEF1A1 GRB2 KDM1A LRIF1 MDM2 SETDB1 SNCA TERF1 TLE1 TRIM26 TRIM55 TRIM63 TULP3 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E2 UBE2H UBE2I UBE2J2 UBE2O UBE2U UBE2V1 UBE2W UBTD1 UTP14A
Entrez ID		63893	9921
HPRD ID		10928	11496
Ensembl ID		ENSG00000175931	ENSG00000022840
Uniprot IDs		Q9C0C9	A0A024RBP0 Q8N5U6
PDB IDs
Enriched GO Terms of Interacting Partners?
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