SDC1 and CD63

Number of citations of the paper that reports this interaction (PubMedID 22660413)
562

Data Source:
BioGRID (pull down)

		SDC1	CD63
Description		syndecan 1	CD63 molecule
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Lumen Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane Cell Surface Protein-containing Complex Lysosomal Lumen Extracellular Exosome	Extracellular Space Nucleoplasm Lysosomal Membrane Plasma Membrane Integral Component Of Plasma Membrane Cell Surface Endosome Membrane Platelet Dense Granule Membrane Intrinsic Component Of Plasma Membrane Late Endosome Membrane Endosome Lumen Multivesicular Body Membrane Azurophil Granule Membrane Melanosome Intracellular Membrane-bounded Organelle Extracellular Exosome Multivesicular Body, Internal Vesicle
	Molecular Function	Protein Binding Protein C-terminus Binding Identical Protein Binding	Protein Binding
	Biological Process	Ureteric Bud Development Inflammatory Response Response To Toxic Substance Cell Migration Wound Healing Odontogenesis Response To Hydrogen Peroxide Myoblast Development Response To Glucocorticoid Response To CAMP Response To Calcium Ion Striated Muscle Cell Development Sertoli Cell Development Canonical Wnt Signaling Pathway Positive Regulation Of Exosomal Secretion Positive Regulation Of Extracellular Exosome Assembly	Positive Regulation Of Receptor Internalization Cell-matrix Adhesion Protein Transport Cell Migration Cellular Protein Localization Endosome To Melanosome Transport Pigment Granule Maturation Regulation Of Vascular Endothelial Growth Factor Signaling Pathway Regulation Of Potassium Ion Transmembrane Transport Positive Regulation Of Integrin-mediated Signaling Pathway
Pathways		A tetrasaccharide linker sequence is required for GAG synthesis HS-GAG biosynthesis HS-GAG biosynthesis HS-GAG degradation Cell surface interactions at the vascular wall Syndecan interactions Syndecan interactions Defective B4GALT7 causes EDS, progeroid type Defective B3GAT3 causes JDSSDHD Defective EXT2 causes exostoses 2 Defective EXT1 causes exostoses 1, TRPS2 and CHDS Defective B3GALT6 causes EDSP2 and SEMDJL1 Other interleukin signaling Retinoid metabolism and transport	Platelet degranulation Neutrophil degranulation
Drugs
Diseases
GWAS		Alanine aminotransferase levels in non-alcoholic fatty liver disease ( 31311600) Amyotrophic lateral sclerosis (sporadic) ( 24529757) Apolipoprotein A1 levels ( 32203549) Body mass index ( 28892062) HDL cholesterol levels ( 32203549) Hip circumference adjusted for BMI ( 34021172) LDL cholesterol levels ( 32203549) Seasonality ( 25562672) Triglyceride levels ( 32203549)	Advanced age-related macular degeneration ( 26691988) Cardiac Troponin-T levels ( 31014085) Refractive error ( 32231278)
Interacting Genes		17 interacting genes: APP CASK CCL5 CD63 CTSG CXCL8 ELANE FGF2 HGF IGFBP7 KEAP1 LACRT MDK MMP14 PTEN PTN SDCBP	18 interacting genes: AP4M1 CD82 CD9 F2RL1 GLP1R HLA-DMB HLA-DRA ITGA6 PI4K2A PTGFRN SDC1 SDCBP SLC22A1 SLC22A2 SRF TIMP1 TMEM80 VKORC1
Entrez ID		6382	967
HPRD ID		01718	01121
Ensembl ID		ENSG00000115884	ENSG00000135404
Uniprot IDs		P18827	A0A024RB05 P08962
PDB IDs		4GVC 4GVD 6EJE
Enriched GO Terms of Interacting Partners?
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