CCL7 and XCL2

Number of citations of the paper that reports this interaction (PubMedID 28381538)
37

Data Source:
BioGRID (pull down)

		CCL7	XCL2
Description		C-C motif chemokine ligand 7	X-C motif chemokine ligand 2
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space	Extracellular Region Extracellular Space
	Molecular Function	Protein Binding Chemokine Activity Heparin Binding CCR1 Chemokine Receptor Binding CCR2 Chemokine Receptor Binding CCR Chemokine Receptor Binding	Protein Binding Chemokine Activity CCR Chemokine Receptor Binding
	Biological Process	Monocyte Chemotaxis Cellular Calcium Ion Homeostasis Chemotaxis Inflammatory Response Cytoskeleton Organization Signal Transduction G Protein-coupled Receptor Signaling Pathway Cell-cell Signaling Regulation Of Cell Shape Response To Gamma Radiation Positive Regulation Of Cell Migration Neutrophil Chemotaxis Positive Regulation Of GTPase Activity Eosinophil Chemotaxis Lymphocyte Chemotaxis Chemokine-mediated Signaling Pathway Positive Regulation Of ERK1 And ERK2 Cascade Cellular Response To Interferon-gamma Cellular Response To Interleukin-1 Cellular Response To Tumor Necrosis Factor Cellular Response To Ethanol Positive Regulation Of Natural Killer Cell Chemotaxis	Monocyte Chemotaxis Inflammatory Response Signal Transduction G Protein-coupled Receptor Signaling Pathway Blood Circulation Positive Regulation Of T Cell Chemotaxis Neutrophil Chemotaxis Positive Regulation Of GTPase Activity Lymphocyte Chemotaxis Chemokine-mediated Signaling Pathway Positive Regulation Of ERK1 And ERK2 Cascade Cellular Response To Interferon-gamma Cellular Response To Interleukin-1 Cellular Response To Tumor Necrosis Factor
Pathways		Chemokine receptors bind chemokines	Chemokine receptors bind chemokines G alpha (q) signalling events
Drugs
Diseases
GWAS		Blood protein levels ( 30072576 29875488) Crohn's disease ( 28067908 22412388 21102463) Gut microbiota (functional units) ( 27694959) Inflammatory bowel disease ( 28067908)	Emphysema imaging phenotypes ( 26030696) Lung cancer ( 28604730) Squamous cell lung carcinoma ( 28604730)
Interacting Genes		20 interacting genes: AATF ACKR1 ACKR2 ACKR4 CCR1 CCR10 CCR3 CCR5 CXCL6 ERBB2 FEZ1 MMP1 MMP13 MMP14 MMP2 MMP3 TLE5 UBQLN1 UBQLN2 XCL2	19 interacting genes: CCL2 CCL20 CCL21 CCL26 CCL28 CCL5 CCL7 CCL8 CXCL12 CXCL17 CXCL2 CXCL3 CXCL5 KRTAP1-3 KRTAP10-9 NOTCH2NLA PF4 PF4V1 XCR1
Entrez ID		6354	6846
HPRD ID		01150	05317
Ensembl ID		ENSG00000108688	ENSG00000143185
Uniprot IDs		P80098	Q9UBD3
PDB IDs		1BO0 1NCV 4ZKC
Enriched GO Terms of Interacting Partners?
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