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RPL5 and CSNK2B
Number of citations of the paper that reports this interaction (PubMedID
14667819
)
36
Data Source:
HPRD
(two hybrid, in vivo, in vitro)
RPL5
CSNK2B
Description
ribosomal protein L5
casein kinase 2 beta
Image
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Nucleolus
Cytoplasm
Endoplasmic Reticulum
Cytosol
Focal Adhesion
Membrane
Cytosolic Large Ribosomal Subunit
Cytosolic Ribosome
Protein-containing Complex
Synapse
Extracellular Exosome
Ribonucleoprotein Complex
Chromatin
Extracellular Region
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
Plasma Membrane
Cilium
Protein Kinase CK2 Complex
Nuclear Matrix
Secretory Granule Lumen
Extracellular Exosome
Ficolin-1-rich Granule Lumen
Molecular Function
RNA Binding
MRNA 3'-UTR Binding
Structural Constituent Of Ribosome
Protein Binding
5S RRNA Binding
Ubiquitin Protein Ligase Binding
MRNA 5'-UTR Binding
Ubiquitin Ligase Inhibitor Activity
Chromatin Binding
Protein Serine/threonine Kinase Activity
Signaling Receptor Binding
Protein Binding
Transcription Factor Binding
Protein Kinase Regulator Activity
Protein Domain Specific Binding
Identical Protein Binding
Ribonucleoprotein Complex Binding
Metal Ion Binding
Biological Process
Ribosomal Large Subunit Assembly
Cytoplasmic Translation
RRNA Processing
Translation
Positive Regulation Of Gene Expression
Ribosomal Large Subunit Biogenesis
Positive Regulation Of Translation
Protein Stabilization
Regulation Of Signal Transduction By P53 Class Mediator
Negative Regulation Of Ubiquitin Protein Ligase Activity
Negative Regulation Of Ubiquitin-dependent Protein Catabolic Process
Negative Regulation Of Protein Neddylation
Signal Transduction
Negative Regulation Of Cell Population Proliferation
Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation
Wnt Signaling Pathway
Peptidyl-threonine Phosphorylation
Positive Regulation Of Activin Receptor Signaling Pathway
Adiponectin-activated Signaling Pathway
Response To Testosterone
Cellular Protein-containing Complex Assembly
Negative Regulation Of Blood Vessel Endothelial Cell Migration
Regulation Of DNA Binding
Endothelial Tube Morphogenesis
Regulation Of Protein Serine/threonine Phosphatase Activity
Liver Regeneration
Pathways
L13a-mediated translational silencing of Ceruloplasmin expression
Peptide chain elongation
SRP-dependent cotranslational protein targeting to membrane
SRP-dependent cotranslational protein targeting to membrane
Viral mRNA Translation
Selenocysteine synthesis
Major pathway of rRNA processing in the nucleolus and cytosol
Formation of a pool of free 40S subunits
GTP hydrolysis and joining of the 60S ribosomal subunit
Eukaryotic Translation Termination
Regulation of expression of SLITs and ROBOs
Response of EIF2AK4 (GCN2) to amino acid deficiency
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Synthesis of PC
WNT mediated activation of DVL
Condensation of Prometaphase Chromosomes
Signal transduction by L1
Neutrophil degranulation
Regulation of TP53 Activity through Phosphorylation
Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding
ROS sensing by NFE2L2
Receptor Mediated Mitophagy
RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known
Regulation of PTEN stability and activity
Drugs
ATP
Quercetin
Diseases
GWAS
Allergic disease (asthma, hay fever or eczema) (
29785011
)
Height (
20881960
)
Mean corpuscular hemoglobin (
32888494
)
Mean reticulocyte volume (
32888494
)
Multiple sclerosis (
19525955
17660530
)
Asthma (
31619474
)
Asthma (childhood onset) (
31619474
)
Asthma and major depressive disorder (
31619474
)
Autism spectrum disorder or schizophrenia (
28540026
)
Blood protein levels (
28240269
)
Cutaneous lupus erythematosus (
25827949
)
Hip circumference adjusted for BMI (
34021172
)
Inflammatory bowel disease (
28067908
)
Malaria (
31844061
)
Systemic lupus erythematosus (
26316170
)
Ulcerative colitis (
28067908
)
Interacting Genes
26 interacting genes:
CLK1
CSNK2A1
CSNK2B
DCC
EIF5A
ERCC6
HARS1
IPO13
IPO5
IPO7
KPNB1
MAP3K14
MDM2
NVL
OGT
PDCD4
PPM1D
RNA5S7
SPIN1
SPP1
TNIP1
TNPO1
TP73
TSC22D1
UPF2
VHL
232 interacting genes:
ABHD4
ACTB
ACTL6B
ACTR1B
ACTR5
ACVRL1
ADD1
ADH5
ANGPT2
ANKRD28
AP2M1
APLP1
ARAF
ATF1
ATG101
ATXN3
BAG6
BANP
BCCIP
BHLHE41
BID
BMI1
BRCA1
BTF3
C6orf136
CACNA1A
CALM1
CBX4
CCDC115
CCDC187
CCNH
CD163
CD81
CDC25B
CDC34
CDK1
CDK20
CDKN1A
CENPB
CHEK1
CHRNA4
CIC
CIP2A
CIPC
CLOCK
COIL
COL4A2
COPS3
COPS7A
CPNE7
CRISP2
CSN1S1
CSN2
CSNK1E
CSNK2A1
CSNK2A2
CST1
CTDP1
CTNNB1
DACT1
DALRD3
DELEC1
DENND5A
DNMT1
DPF3
DUX1
DYNLT2B
EIF2S2
EIF5
EIF6
EPS8
ERCC6
ERCC8
ESR1
FAF1
FAM86C1P
FBXL15
FBXL5
FGB
FGF1
FGF2
FIBP
FKBP3
FTH1
FXR1
FXR2
GADD45GIP1
GAMT
GBP2
GLB1
GLIS2
GNB5
GRIN2A
GRIN2B
GRK2
GSK3B
GTPBP2
HEXB
HNRNPA2B1
HOXB5
HOXB6
HTRA1
HYPK
IER3IP1
INO80B
INTS11
IRS1
ITSN1
KCNA3
KDM6B
KIF2C
LCK
LEPR
LMO4
LRP5L
LTB4R2
LYN
LYST
MAPK14
MBD4
MDM2
MME
MOXD1
MPP2
NAP1L1
NCF1
NGDN
NMT2
NOLC1
NOTCH3
NPAS2
NRBP1
NRF1
NTAQ1
ODC1
OGA
OGT
PDS5A
PER1
PER2
PFKFB4
PHC2
PHF11
PIMREG
PIN1
PITPNA
PLXNA3
POT1
PPID
PPP1CA
PPP1CB
PPP1CC
PPP2CA
PPP2R1A
PPP2R1B
PPP2R5D
PPP2R5E
PPP3CC
PRKAB2
PRKCZ
PRNP
PROC
PTPRK
PTTG2
PYROXD2
RAD51
RBM39
RFC1
RNF126
RNF7
RORB
RPA1
RPL13
RPL41
RPL5
RPS6KA5
RPS6KB1
RPS6KB2
RRAD
RXRA
SARNP
SDHA
SEC11A
SELENOI
SHANK3
SHMT1
SHMT2
SIMC1
SIRT1
SNX2
SPOUT1
SPSB3
SSB
STAT5A
STAU1
STK16
SUMO2
SYNE4
TCEAL7
TENM1
TFAP2A
TFAP2D
TLE1
TLX3
TNFAIP1
TOP2B
TP53
TP53BP2
TP63
TRIM27
TRIM54
TSEN54
TUBB2B
TWF1
UBE2I
UPF1
USO1
UTP14A
VDAC1
VRK3
WDR1
WDR18
WFIKKN1
WWOX
ZFP36L1
ZNF19
ZNF410
ZNF44
ZNF71
ZNF76
ZNF784
ZNHIT1
Entrez ID
6125
1460
HPRD ID
04699
00278
Ensembl ID
ENSG00000122406
ENSG00000204435
Uniprot IDs
A2RUM7
P46777
A0A1U9X7J2
N0E4C7
P67870
PDB IDs
4UG0
4V6X
5AJ0
5LKS
5T2C
6EK0
6IP5
6IP6
6IP8
6LQM
6LSR
6LSS
6LU8
6OLE
6OLF
6OLG
6OLI
6OLZ
6OM0
6OM7
6QZP
6W6L
6XA1
6Y0G
6Y2L
6Y57
6Y6X
6Z6L
6Z6M
6Z6N
6ZM7
6ZME
6ZMI
6ZMO
7BHP
1DS5
1JWH
1QF8
3EED
4DGL
4MD7
4MD8
4MD9
4NH1
6Q38
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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