PAPPA2 and ZNF512B

Number of citations of the paper that reports this interaction (PubMedID 15231748)
99

Data Source:
BioGRID (two hybrid)

		PAPPA2	ZNF512B
Description		pappalysin 2	zinc finger protein 512B
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Cytosol Apical Plasma Membrane Extracellular Exosome	Nucleoplasm
	Molecular Function	Metalloendopeptidase Activity Metallopeptidase Activity Zinc Ion Binding	DNA Binding Protein Binding Metal Ion Binding
	Biological Process	Regulation Of Cell Growth Proteolysis Response To Salt Stress Cellular Protein Metabolic Process Bone Morphogenesis
Pathways		Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)	RHOV GTPase cycle
Drugs
Diseases
GWAS		Apolipoprotein A1 levels ( 32203549) Automobile speeding propensity ( 30643258) Birth weight ( 31043758) Body mass index ( 26426971) Fractional exhaled nitric oxide (childhood) ( 24315451) GIP levels in response to oral glucose tolerance test (120 minutes) ( 29093273) Height ( 20881960 25429064 31562340) Hip circumference adjusted for BMI ( 34021172) Offspring birth weight ( 31043758) Pediatric central nervous system tumors (late onset)(pleiotropy) ( 33226468) Pediatric central nervous system tumors (pleiotropy) ( 33226468) Perioperative myocardial infarction in coronary artery bypass surgery ( 25948407) Pulse pressure ( 27841878 30578418) Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction) ( 28448500) Waist-to-hip ratio adjusted for BMI in inactive individuals ( 28448500) Waist-to-hip ratio adjusted for body mass index ( 28448500)	Birth weight ( 31043758) Mean platelet volume ( 32888494) Offspring birth weight ( 31043758) Prostate cancer ( 23535732) Serum alkaline phosphatase levels ( 33547301)
Interacting Genes		5 interacting genes: ATF7IP IGFBP3 IGFBP5 SMAD4 ZNF512B	71 interacting genes: AJUBA ANKLE2 ANKRD28 AP1G1 APLP2 ATRX BANP BRD1 BTBD2 C11orf68 CDC123 CREBZF CTBP2 DCTN1 DDX3X DROSHA DVL3 EHMT2 FHL3 GLRX3 GOLGA2 HEYL HTATSF1 IL36RN INVS KDM2A KDM3B KLF10 KMT2B L1TD1 LAMB2 LZTS2 MBD1 MDFI MEOX2 MTUS2 MYH10 NACC1 NIBAN2 OS9 PAPPA2 PBRM1 PDE4DIP PEG10 PIAS4 PLCG2 PPP1R15A PTPRF RABEP1 RPS27A SDF4 SIAH1 SMAD1 SPTBN1 SUPT5H TGM2 TNKS2 TOM1 TOX4 TRAF1 TRAF4 VHL VPS35 VPS41 VWF XPC XRCC6 YES1 ZMYM2 ZNF143 ZYX
Entrez ID		60676	57473
HPRD ID		10156	13840
Ensembl ID		ENSG00000116183	ENSG00000196700
Uniprot IDs		Q9BXP8	Q96KM6
PDB IDs			2GQJ
Enriched GO Terms of Interacting Partners?
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