RNF6 and KIAA0753

Number of citations of the paper that reports this interaction (PubMedID 26871637)
172

Data Source:
BioGRID (two hybrid)

		RNF6	KIAA0753
Description		ring finger protein 6	KIAA0753
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm PML Body Axon Nuclear Membrane Intracellular Membrane-bounded Organelle	Centrosome Centriole Cytosol Centriolar Satellite
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding Metal Ion Binding Androgen Receptor Binding Ubiquitin Protein Ligase Activity	Protein Binding
	Biological Process	Regulation Of Transcription, DNA-templated Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination Negative Regulation Of Axon Extension Protein K27-linked Ubiquitination Positive Regulation Of Transcription, DNA-templated Regulation Of Androgen Receptor Signaling Pathway Protein K48-linked Ubiquitination Protein K6-linked Ubiquitination	Centriole Replication Protein Localization To Centrosome
Pathways		Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Sporadic pituitary adenoma ( 26029870) Type 2 diabetes ( 24509480 30297969 32499647 30718926 28869590) Urate levels (BMI interaction) ( 25811787)	Familial lung cancer ( 29924316) LDL cholesterol levels x thiazide or thiazide-like diuretics use interaction ( 31806883) Pulse pressure ( 28135244 27841878 30578418) Systolic blood pressure ( 27841878 30578418)
Interacting Genes		36 interacting genes: AHCYL1 AR CBY2 CCDC33 CCDC57 CEP70 GOLGA2 HOOK2 IKZF1 IKZF3 KIAA0753 KRT15 KRT40 LDOC1 MAGED1 MDFI MEOX2 MID2 MIPOL1 MTUS2 PNMA2 REL RINT1 RPGRIP1 SSX2IP STX11 TADA2A TCF4 TFIP11 TNS2 TRIM23 TRIM27 TRIM37 TSGA10 UBE2D1 UBE2H	20 interacting genes: AARD BHLHA9 BRPF1 C1orf109 CCHCR1 CT55 FAM161A GCC1 HGS KIFC3 MNS1 RNF6 ROPN1 SMARCD1 SUOX TCHP TEAD4 USHBP1 ZNF114 ZNF777
Entrez ID		6049	9851
HPRD ID		05027	11106
Ensembl ID		ENSG00000127870	ENSG00000198920
Uniprot IDs		A0A024RDP2 A0A0S2Z4G9 Q9Y252	Q2KHM9
PDB IDs
Enriched GO Terms of Interacting Partners?
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