RGS3 and DEPDC1B

Number of citations of the paper that reports this interaction (PubMedID 25458010)
29

Data Source:
BioGRID (two hybrid)

		RGS3	DEPDC1B
Description		regulator of G protein signaling 3	DEP domain containing 1B
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol Plasma Membrane
	Molecular Function	GTPase Activity GTPase Activator Activity Protein Binding	GTPase Activator Activity
	Biological Process	Signal Transduction G Protein-coupled Receptor Signaling Pathway Regulation Of G Protein-coupled Receptor Signaling Pathway Negative Regulation Of Signal Transduction Regulation Of Catalytic Activity	Cell Migration Positive Regulation Of Wnt Signaling Pathway Intracellular Signal Transduction Regulation Of Catalytic Activity
Pathways		G alpha (q) signalling events G alpha (i) signalling events	RHOA GTPase cycle RHOB GTPase cycle RHOC GTPase cycle CDC42 GTPase cycle RAC1 GTPase cycle RAC2 GTPase cycle RHOD GTPase cycle RHOQ GTPase cycle RHOG GTPase cycle RHOJ GTPase cycle RHOU GTPase cycle RAC3 GTPase cycle RHOV GTPase cycle RHOF GTPase cycle RND3 GTPase cycle RND2 GTPase cycle RND1 GTPase cycle
Drugs
Diseases
GWAS		Height ( 28552196) Hematocrit ( 32888494) Hemoglobin ( 32888494) Hemoglobin levels ( 32327693) Red blood cell count ( 32888494) Refractive error ( 32231278)	Autism spectrum disorder or schizophrenia ( 28540026) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Intelligence (MTAG) ( 29326435) Metabolite levels ( 23823483) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		25 interacting genes: ACD APP CDK6 CNKSR2 CYSRT1 DEPDC1B EFNB1 EFNB2 ESR1 GLS2 GNA11 GNAI3 GORASP2 GRIN2A HES4 HIPK3 MAPK12 PAX6 PLSCR1 PRKN SCN5A YWHAB YWHAE YWHAQ YWHAZ	6 interacting genes: CDC23 EBPL GRIP1 PTPRF RGS3 UHMK1
Entrez ID		5998	55789
HPRD ID		03720	16794
Ensembl ID		ENSG00000138835	ENSG00000035499
Uniprot IDs		A0A024R831 A0A024R833 A0A024R841 B3KVT7 B3KWG8 H7BXY1 P49796 Q53GP3	Q8WUY9
PDB IDs		2F5Y 2OJ4 3FBK
Enriched GO Terms of Interacting Partners?
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