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UPF1 and MIR29B1
Number of citations of the paper that reports this interaction (PubMedID
28431233
)
92
Data Source:
BioGRID
(unspecified method)
UPF1
MIR29B1
Description
UPF1 RNA helicase and ATPase
microRNA 29b-1
Image
No pdb structure
GO Annotations
Cellular Component
Chromosome, Telomeric Region
Chromatin
P-body
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
Exon-exon Junction Complex
Supraspliceosomal Complex
Extracellular Space
Nucleus
Cytoplasm
Mitochondrion
Extracellular Exosome
Extracellular Vesicle
Molecular Function
Chromatin Binding
RNA Binding
RNA Helicase Activity
Helicase Activity
Protein Binding
ATP Binding
Zinc Ion Binding
Hydrolase Activity
Telomeric DNA Binding
MRNA 3'-UTR Binding
MRNA Binding Involved In Posttranscriptional Gene Silencing
Biological Process
Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay
Nuclear-transcribed MRNA Catabolic Process, Endonucleolytic Cleavage-dependent Decay
Nuclear-transcribed MRNA Catabolic Process
DNA Replication
DNA Repair
MRNA Export From Nucleus
Regulation Of Translational Termination
Dosage Compensation By Inactivation Of X Chromosome
Telomere Maintenance Via Semi-conservative Replication
Regulation Of Telomere Maintenance
Cell Cycle Phase Transition
Positive Regulation Of MRNA Catabolic Process
3'-UTR-mediated MRNA Destabilization
Histone MRNA Catabolic Process
Cellular Response To Lipopolysaccharide
Cellular Response To Interleukin-1
Negative Regulation Of Cytokine-mediated Signaling Pathway
Negative Regulation Of Cell Population Proliferation
Positive Regulation Of Gene Expression
Negative Regulation Of Gene Expression
Negative Regulation Of Epithelial To Mesenchymal Transition
Positive Regulation Of Triglyceride Biosynthetic Process
Positive Regulation Of Cell Migration
Negative Regulation Of Cell Migration
Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Negative Regulation Of Collagen Biosynthetic Process
Negative Regulation Of Type III Interferon Production
Gene Silencing By MiRNA
MiRNA Mediated Inhibition Of Translation
Positive Regulation Of Apoptotic Process
Negative Regulation Of MAPK Cascade
Regulation Of DNA Methylation
Positive Regulation Of Fat Cell Differentiation
Negative Regulation Of Epithelial Cell Proliferation
Negative Regulation Of Protein Secretion
Negative Regulation Of Protein Kinase B Signaling
Regulation Of Membrane Repolarization
Regulation Of Blood Vessel Remodeling
Negative Regulation Of Circulating Fibrinogen Levels
Negative Regulation Of Canonical Wnt Signaling Pathway
Cellular Response To Virus
Negative Regulation Of Interleukin-32 Production
Negative Regulation Of Extracellular Matrix Assembly
Negative Regulation Of NIK/NF-kappaB Signaling
Positive Regulation Of Mitochondrial Membrane Permeability Involved In Apoptotic Process
Negative Regulation Of Amyloid-beta Formation
Negative Regulation Of Mesenchymal Stem Cell Proliferation
Negative Regulation Of Amyloid Precursor Protein Catabolic Process
Negative Regulation Of Oxidative Stress-induced Cell Death
Negative Regulation Of Voltage-gated Potassium Channel Activity
Negative Regulation Of Cellular Response To Transforming Growth Factor Beta Stimulus
Regulation Of Aorta Morphogenesis
Negative Regulation Of Collagen Fibril Organization
Negative Regulation Of Matrix Metallopeptidase Secretion
Positive Regulation Of Metalloendopeptidase Activity
Regulation Of Epithelium Regeneration
Negative Regulation Of Metallopeptidase Activity
Positive Regulation Of Canonical Wnt Signaling Pathway Involved In Osteoblast Differentiation
Negative Regulation Of Intestinal Epithelial Cell Development
Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle
Pathways
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS
Attention deficit hyperactivity disorder (
32595297
)
Pancreatic cancer (
25086665
)
Waist-to-hip ratio adjusted for BMI (age >50) (
26426971
)
Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) (
26426971
)
Interacting Genes
109 interacting genes:
ABHD16A
ACRV1
ACSS2
AP1G1
ATR
CNN1
CSNK2B
DCP1A
DCP2
DHPS
DXO
EIF3A
EIF3B
EIF4A3
EXOSC2
EXOSC4
GNPTG
HIRA
LDB1
LSM8
MIR1-1
MIR1-2
MIR106A
MIR106B
MIR107
MIR10B
MIR122
MIR128-1
MIR128-2
MIR138-1
MIR138-2
MIR140
MIR141
MIR143
MIR145
MIR155
MIR15A
MIR15B
MIR16-1
MIR16-2
MIR17
MIR18A
MIR18B
MIR199A1
MIR199A2
MIR19A
MIR19B1
MIR19B2
MIR200A
MIR200B
MIR200C
MIR205
MIR206
MIR20A
MIR20B
MIR21
MIR214
MIR221
MIR222
MIR25
MIR29A
MIR29B1
MIR29B2
MIR29C
MIR31
MIR34A
MIR34B
MIR34C
MIR363
MIR429
MIR451A
MIR7-1
MIR7-2
MIR7-3
MIR9-1
MIR9-3
MIR92A1
MIR92A2
MIR93
MIR98
MIRLET7A1
MIRLET7A2
MIRLET7A3
MIRLET7B
MIRLET7C
MIRLET7D
MIRLET7E
MIRLET7F1
MIRLET7F2
MIRLET7G
MIRLET7I
NADSYN1
NDRG1
NDUFB10
NOTCH3
PLEKHA5
PLEKHB2
POLR2A
PTEN
RHOXF2
RPRD2
SMG1
SMG5
STAU1
SUMO2
UPF2
UPF3A
UPF3B
XRN1
72 interacting genes:
APOBEC3B
C1QBP
DARS1
DDX1
DDX21
DDX3X
DHX36
EIF2AK2
EPRS1
FAM98A
FUS
G3BP2
HARS2
HNRNPA0
HNRNPA1
HNRNPA2B1
HNRNPA3
HNRNPF
HNRNPH1
HNRNPH2
HNRNPH3
HNRNPK
HNRNPL
HNRNPM
HNRNPR
IGF2BP1
IGF2BP2
IGF2BP3
KARS1
KNOP1
LARP7
LIN28A
LIN28B
LRPPRC
MARS1
MATR3
MSI1
MSI2
MYEF2
NOL6
NONO
PDCD11
PLOD1
PRMT1
PTBP1
PTBP3
PUF60
PURA
RBFOX2
RBM14
RBM4
RBM47
RBMS2
RTCB
SF3B1
SF3B3
SFPQ
SPOUT1
STRBP
SUGP2
SYNCRIP
TAF15
TRA2A
TRA2B
TRIM25
TRIM71
UPF1
UTP20
YBX1
YBX3
ZFR
ZNF346
Entrez ID
5976
407024
HPRD ID
03254
Ensembl ID
ENSG00000005007
ENSG00000283797
Uniprot IDs
A0A024R7L5
A0A024R7L8
B3KY55
Q92900
PDB IDs
2GJK
2GK6
2GK7
2IYK
2WJV
2WJY
2XZO
2XZP
6EJ5
6Z3R
Enriched GO Terms of Interacting Partners
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