PLEKHA2 and MPDZ

Number of citations of the paper that reports this interaction (PubMedID 11802782)
37

Data Source:
BioGRID (two hybrid, affinity chromatography technology)

		PLEKHA2	MPDZ
Description		pleckstrin homology domain containing A2	multiple PDZ domain crumbs cell polarity complex component
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Plasma Membrane Membrane Protein-containing Complex	Cytoplasm Plasma Membrane Bicellular Tight Junction Postsynaptic Density Apical Plasma Membrane Apicolateral Plasma Membrane Dendrite Apical Part Of Cell
	Molecular Function	Fibronectin Binding Protein Binding Lipid Binding PDZ Domain Binding Laminin Binding Phosphatidylinositol-3,4-bisphosphate Binding	Protein Binding Protein C-terminus Binding
	Biological Process	Positive Regulation Of Cell-matrix Adhesion	Microtubule Organizing Center Organization Regulation Of Microtubule Cytoskeleton Organization Tight Junction Assembly
Pathways		Synthesis of PIPs at the plasma membrane
Drugs
Diseases
GWAS		High density lipoprotein cholesterol levels ( 31211820) Monocyte percentage of white cells ( 32888494)	Central corneal thickness ( 32528159 29760442) Corneal hysteresis ( 32716492 30894546) Corneal structure ( 23291589) Heel bone mineral density ( 30598549 28869591) Refractive astigmatism ( 30306274) Triglyceride levels ( 32203549)
Interacting Genes		19 interacting genes: COG6 DLG2 DLG3 EGLN3 FHL5 GIPC1 GIPC2 GIPC3 GOLGA2 HSF2BP KANK2 LNX1 M1AP MPDZ PLEKHA1 PTPN13 SNTG1 TEPSIN TRIM23	16 interacting genes: ABCA1 CAMK2A CLDN1 CLDN5 CRHR1 CSPG4 DRD3 F11R HTR2C KIT MTNR1A PLEKHA1 PLEKHA2 RNF5 SYNGAP1 TSC22D2
Entrez ID		59339	8777
HPRD ID			09155
Ensembl ID		ENSG00000169499	ENSG00000107186
Uniprot IDs		A0A087WZ32 A8K727 Q9HB19	O75970
PDB IDs			2FCF 2FNE 2IWN 2IWO 2IWP 2IWQ 2O2T 2OPG 2QG1
Enriched GO Terms of Interacting Partners?
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