RBBP4 and LIN9

Number of citations of the paper that reports this interaction (PubMedID 28514442)
406

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology)

		RBBP4	LIN9
Description		RB binding protein 4, chromatin remodeling factor	lin-9 DREAM MuvB core complex component
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GO Annotations	Cellular Component	Histone Deacetylase Complex Chromatin Nucleus Nucleoplasm Cytosol Sin3 Complex NuRD Complex NURF Complex Protein-containing Complex CAF-1 Complex ESC/E(Z) Complex	Nucleoplasm Transcription Repressor Complex
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Protein Binding ATP-dependent Activity, Acting On DNA Nucleosomal DNA Binding Histone Binding Histone Deacetylase Binding	DNA Binding Protein Binding
	Biological Process	DNA Replication DNA Replication-dependent Nucleosome Assembly DNA Replication-independent Nucleosome Assembly Chromatin Remodeling Cell Cycle Negative Regulation Of Cell Population Proliferation Chromatin Assembly	Reproduction Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Cell Cycle Regulation Of Cell Cycle DNA Biosynthetic Process
Pathways		Transcription of E2F targets under negative control by DREAM complex Transcription of E2F targets under negative control by DREAM complex Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 G0 and Early G1 Polo-like kinase mediated events PRC2 methylates histones and DNA Oxidative Stress Induced Senescence HDACs deacetylate histones PKMTs methylate histone lysines ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression Activation of anterior HOX genes in hindbrain development during early embryogenesis Deposition of new CENPA-containing nucleosomes at the centromere Regulation of TP53 Activity through Acetylation Cyclin E associated events during G1/S transition G1/S-Specific Transcription Cyclin A:Cdk2-associated events at S phase entry RNA Polymerase I Transcription Initiation Regulation of PTEN gene transcription Regulation of PTEN gene transcription Transcriptional Regulation by E2F6 HCMV Early Events Potential therapeutics for SARS Defective pyroptosis	Transcription of E2F targets under negative control by DREAM complex Transcription of E2F targets under negative control by DREAM complex Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 G0 and Early G1 Polo-like kinase mediated events Cyclin E associated events during G1/S transition G1/S-Specific Transcription Cyclin A:Cdk2-associated events at S phase entry
Drugs
Diseases
GWAS			Caudate nucleus volume ( 31530798) Gut microbiota beta diversity (weighted UniFrac distance) ( 33208821) Mean corpuscular hemoglobin ( 32888494) Mean platelet volume ( 32888494) Nicotine dependence symptom count ( 25555482)
Interacting Genes		63 interacting genes: AEBP2 ANXA7 ARMC12 BCL11A BCL11B BRCA1 BRMS1 BRMS1L CDKN1A CHAF1B CREB1 CREBBP CYTOR DHX30 ERCC6 ESR1 FOXK2 H1-1 H2AC20 H3-4 H3C1 H3C14 H4-16 H4C14 HDAC1 HDAC2 HDAC3 HDAC4 HMOX2 ING1 KPNA3 KPNA5 LIN9 LMNA MBD2 MBD3 MBD3L2 MTA1 MTA2 MYBL2 NR2E3 OGT PRDM16 RB1 RBBP7 RBP1 RPN1 RPN2 RYBP SALL4 SAP30 SIN3A SMN1 SP1 SP3 SPEN STAT5B SUMO2 SUV39H1 SUZ12 TK1 TSSK3 XRCC6	3 interacting genes: MYBL2 RB1 RBBP4
Entrez ID		5928	286826
HPRD ID		04232	13990
Ensembl ID		ENSG00000162521	ENSG00000183814
Uniprot IDs		Q09028	Q5TKA1 Q6P142
PDB IDs		2XU7 3GFC 4PBY 4PBZ 4PC0 4R7A 5FXY 5VTB 5WAI 5WAK 5XWR 5XXQ 5Y1U 6BW3 6BW4 6C23 6C24 6G16 6NQ3 6WKR 6ZRC 6ZRD 7AOA 7KSO 7KSR 7KTP	6C48
Enriched GO Terms of Interacting Partners?
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