ACTA2 and CCT5

Number of citations of the paper that reports this interaction (PubMedID 11580270)
19

Data Source:
HPRD (in vitro)

		ACTA2	CCT5
Description		actin alpha 2, smooth muscle	chaperonin containing TCP1 subunit 5
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Space Cytoplasm Cytosol Dynactin Complex Lamellipodium Filopodium Smooth Muscle Contractile Fiber Protein-containing Complex Cell Body Extracellular Exosome	Centrosome Cytosol Chaperonin-containing T-complex Microtubule Cell Body Extracellular Exosome
	Molecular Function	ATP Binding Protein Kinase Binding	MRNA 3'-UTR Binding Protein Binding ATP Binding G-protein Beta-subunit Binding Protein Folding Chaperone MRNA 5'-UTR Binding Beta-tubulin Binding Unfolded Protein Binding
	Biological Process	Regulation Of Blood Pressure Response To Virus Positive Regulation Of Gene Expression Vascular Associated Smooth Muscle Contraction Glomerular Mesangial Cell Development Mesenchyme Migration	Protein Folding Binding Of Sperm To Zona Pellucida Response To Virus Positive Regulation Of Telomere Maintenance Via Telomerase Protein Stabilization Toxin Transport Positive Regulation Of Establishment Of Protein Localization To Telomere Positive Regulation Of Protein Localization To Cajal Body Positive Regulation Of Telomerase RNA Localization To Cajal Body
Pathways		Smooth Muscle Contraction NOTCH4 Intracellular Domain Regulates Transcription	Prefoldin mediated transfer of substrate to CCT/TriC Formation of tubulin folding intermediates by CCT/TriC Folding of actin by CCT/TriC Association of TriC/CCT with target proteins during biosynthesis Association of TriC/CCT with target proteins during biosynthesis BBSome-mediated cargo-targeting to cilium Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding
Drugs		Phenethyl Isothiocyanate
Diseases
GWAS		Arthritis (juvenile idiopathic) ( 33106285) Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007) Chronic lymphocytic leukemia ( 26956414 23770605) Immunoglobulin A ( 20694011) Lymphocyte percentage of white cells ( 32888494) Pulse pressure ( 30578418) Selective IgA deficiency ( 27723758)	Metabolite levels ( 23823483) Pain ( 22956598)
Interacting Genes		18 interacting genes: CCT4 CCT5 CFL1 CREBBP DNASE1 EP300 GC MINK1 MYL1 MYOC PCYT1B PRKCD SELE SHBG SNTA1 TMSB4X UBE3A YBX1	21 interacting genes: ACTA1 ACTA2 ACTB CDC20 DUXAP9 ELP1 ERCC6 HDAC3 IMMT MCPH1 OGT PDCL SUMO2 SUMO4 TBC1D17 TCP1 TERT THEG TP53 XRN1 ZNRD2
Entrez ID		59	22948
HPRD ID		00031	06468
Ensembl ID		ENSG00000107796	ENSG00000150753
Uniprot IDs		D2JYH4 P62736	B4DDU6 B4DX08 B4DYC8 B7ZAR1 E7ENZ3 E9PCA1 P48643 V9HW37
PDB IDs			5UYX 5UYZ 6NR8 6NR9 6NRA 6NRB 6NRC 6NRD 6QB8 7LUM 7LUP
Enriched GO Terms of Interacting Partners?
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