RAB27A and SYTL2

Number of citations of the paper that reports this interaction (PubMedID 11773082)
58

Data Source:
HPRD (in vitro, in vivo)

		RAB27A	SYTL2
Description		RAB27A, member RAS oncogene family	synaptotagmin like 2
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GO Annotations	Cellular Component	Photoreceptor Outer Segment Extracellular Region Lysosome Late Endosome Golgi Apparatus Cytosol Apical Plasma Membrane Secretory Granule Dendrite Secretory Granule Membrane Multivesicular Body Membrane Weibel-Palade Body Melanosome Membrane Specific Granule Lumen Melanosome Extracellular Exosome Exocytic Vesicle	Cytoplasm Plasma Membrane Membrane Extrinsic Component Of Plasma Membrane Melanosome Exocytic Vesicle
	Molecular Function	GTPase Activity G Protein Activity Protein Binding GTP Binding GDP Binding Protein Domain Specific Binding Myosin V Binding	Phosphatidylserine Binding Protein Binding Phosphatidylinositol-4,5-bisphosphate Binding Phosphatase Binding Small GTPase Binding Neurexin Family Protein Binding
	Biological Process	Protein Targeting Exocytosis Blood Coagulation Positive Regulation Of Gene Expression Antigen Processing And Presentation Melanocyte Differentiation Melanosome Localization Melanosome Transport Multivesicular Body Organization Cytotoxic T Cell Degranulation Natural Killer Cell Degranulation Positive Regulation Of Exocytosis Synaptic Vesicle Transport Positive Regulation Of Phagocytosis Multivesicular Body Sorting Pathway Complement-dependent Cytotoxicity Positive Regulation Of Regulated Secretory Pathway Positive Regulation Of Reactive Oxygen Species Biosynthetic Process Positive Regulation Of Constitutive Secretory Pathway Exosomal Secretion	Intracellular Protein Transport Exocytosis Vesicle Docking Involved In Exocytosis Vesicle-mediated Transport
Pathways		Insulin processing Neutrophil degranulation RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs
Drugs
Diseases
GWAS		Fractional exhaled nitric oxide levels ( 25431337) Glioma ( 30714141)	Pallidum volume ( 31530798) Refractive error ( 32231278)
Interacting Genes		29 interacting genes: ADRB2 APP BACE2 CEP126 COPS6 EEF1A1 ERG28 EXPH5 GDF9 GDI1 GZMB LRIF1 MLPH MYO5A MYRIP RABGGTB RBM48 RIMS1 RIMS2 RPH3A RPH3AL STX1A SYTL1 SYTL2 SYTL3 SYTL4 SYTL5 UNC13D ZBTB16	9 interacting genes: FBXO25 LNX1 MORN4 MTERF1 NRXN1 PPP1CA RAB27A RAB27B YIF1A
Entrez ID		5873	54843
HPRD ID		04845	10260
Ensembl ID		ENSG00000069974	ENSG00000137501
Uniprot IDs		A2RU94 P51159	A0A0U1RR07 Q9HCH5
PDB IDs		6HUF	3BC1
Enriched GO Terms of Interacting Partners?
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