BCAT2 and ALDOA

Number of citations of the paper that reports this interaction (PubMedID 21988832)
87

Data Source:
BioGRID (two hybrid)

		BCAT2	ALDOA
Description		branched chain amino acid transaminase 2	aldolase, fructose-bisphosphate A
Image
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Matrix	Extracellular Region Extracellular Space Nucleus Cytosol Actin Cytoskeleton Membrane Platelet Alpha Granule Lumen M Band I Band Secretory Granule Lumen Sperm Head Extracellular Exosome Tertiary Granule Lumen Ficolin-1-rich Granule Lumen
	Molecular Function	Branched-chain-amino-acid Transaminase Activity L-leucine:2-oxoglutarate Aminotransferase Activity L-leucine Transaminase Activity L-valine Transaminase Activity L-isoleucine Transaminase Activity	RNA Binding Actin Binding Fructose-bisphosphate Aldolase Activity Protein Binding Cytoskeletal Protein Binding Tubulin Binding Identical Protein Binding Cadherin Binding Fructose Binding
	Biological Process	Isoleucine Catabolic Process Branched-chain Amino Acid Biosynthetic Process Leucine Biosynthetic Process Valine Biosynthetic Process Regulation Of Hormone Levels Cellular Response To Leukemia Inhibitory Factor	Fructose Metabolic Process Glycolytic Process ATP Biosynthetic Process Striated Muscle Contraction Actin Filament Organization Binding Of Sperm To Zona Pellucida Regulation Of Cell Shape Fructose 1,6-bisphosphate Metabolic Process Muscle Cell Cellular Homeostasis Protein Homotetramerization
Pathways		Branched-chain amino acid catabolism	Platelet degranulation Neutrophil degranulation Glycolysis Gluconeogenesis
Drugs		Pyridoxal phosphate Glutamic acid Leucine Isoleucine Pyridoxamine-5'-Phosphate N-[O-Phosphono-Pyridoxyl]-Isoleucine alpha-Ketoisovalerate	Zinc 1,6-Fructose Diphosphate (Linear Form) Dihydroxyacetone phosphate 1,6-DI-O-PHOSPHONO-D-MANNITOL N-(4-CHLOROPHENYL)-3-(PHOSPHONOOXY)NAPHTHALENE-2-CARBOXAMIDE Artenimol Zinc acetate Zinc chloride Zinc sulfate, unspecified form
Diseases
GWAS		Long-term memory (delayed word recall task) ( 29970928) Resting metabolic rate ( 28476931) Serum metabolite levels ( 33031748)	Autism spectrum disorder or schizophrenia ( 28540026) Body fat distribution (arm fat ratio) ( 30664634) Brain morphology (MOSTest) ( 32665545) Cataracts ( 34127677) Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143) Medication use (agents acting on the renin-angiotensin system) ( 31015401) Monocyte count ( 32888494) Plateletcrit ( 32888494) Schizophrenia ( 25056061 29483656)
Interacting Genes		4 interacting genes: ALDOA APP CREB3 PTGDS	35 interacting genes: ADRB2 ALDOB ATP6V1E1 BCAT2 CACNA1A CYTH2 DYNLL1 EGFR ENO1 ENO3 ERBB2 ERBB3 ERBB4 FANCA GALNT6 GPD2 HSD17B10 HSPB2 IFNA4 LINC01554 MLH1 MYOC OGT PCNA PIAS4 PLD2 SHANK3 SLC22A1 SRPK2 SUMO4 TERF1 TGM2 TRIM63 TUBB XRN1
Entrez ID		587	226
HPRD ID		00217	00070
Ensembl ID		ENSG00000105552	ENSG00000149925
Uniprot IDs		B3KSI3 O15382	P04075 V9HWN7
PDB IDs		1EKF 1EKP 1EKV 1KT8 1KTA 2A1H 2HDK 2HG8 2HGW 2HGX 2HHF 5BWR 5BWT 5BWU 5BWV 5BWW 5BWX 5CR5 5HNE 5I5S 5I5T 5I5U 5I5V 5I5W 5I5X 5I5Y 5I60 5MPR 6PRX	1ALD 2ALD 4ALD 5KY6
Enriched GO Terms of Interacting Partners?
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