RAB4A and RUFY1

Number of citations of the paper that reports this interaction (PubMedID 11172003)
36

Data Source:
HPRD (two hybrid)

		RAB4A	RUFY1
Description		RAB4A, member RAS oncogene family	RUN and FYVE domain containing 1
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GO Annotations	Cellular Component	Endosome Cytosol Plasma Membrane Cytoplasmic Vesicle Membrane Early Endosome Membrane Vesicle Insulin-responsive Compartment Perinuclear Region Of Cytoplasm Recycling Endosome Membrane Extracellular Exosome Postsynaptic Recycling Endosome Anchored Component Of Synaptic Vesicle Membrane	Cytoplasm Endosome Cytosol Nuclear Speck Early Endosome Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	ATPase Activator Activity GTPase Activity G Protein Activity Protein Binding GTP Binding GDP Binding Syntaxin Binding Ionotropic Glutamate Receptor Binding ATPase Binding	Protein Binding Lipid Binding SH3 Domain Binding SH2 Domain Binding Metal Ion Binding
	Biological Process	Protein Transport Antigen Processing And Presentation Regulation Of Endocytosis Rab Protein Signal Transduction Regulation Of Catalytic Activity	Endocytosis Small GTPase Mediated Signal Transduction Protein Transport Regulation Of Endocytosis
Pathways		Translocation of SLC2A4 (GLUT4) to the plasma membrane Synthesis of PIPs at the plasma membrane TBC/RABGAPs RAB geranylgeranylation MET receptor recycling	Synthesis of PIPs at the plasma membrane
Drugs
Diseases
GWAS		Aging ( 22773346) Leukoderma in response to rhododendrol ( 32558222) Mean arterial pressure (alcohol consumption interaction) ( 24376456) Mercury levels ( 26025379) Response to antidepressants in depression ( 27622933)	Daytime sleep phenotypes ( 27126917) Dental caries (decayed and filled deciduous teeth) ( 31533690) Eating disorders ( 22911880) Lung cancer ( 28604730) Monocyte percentage of white cells ( 32888494) TPE interval (resting) ( 32386560)
Interacting Genes		33 interacting genes: ACTB APBB3 CD2AP CDK1 CHM DYNC1LI1 DYNLL1 EXOC5 FAM71C GDI2 GRIPAP1 HACE1 IDH3A KCTD7 KIF3B MAPK3 PIN1 PRKCI PTTG1IP RAB11FIP1 RAB7A RABAC1 RABEP1 RABEP2 RABGAP1 RABGEF1 RBSN RUFY1 SOD2 STX4 TP53 VPS52 ZNF830	18 interacting genes: AP3B2 AP3D1 AP3M1 AP3S1 BMX EPHA3 GIT2 ITSN2 OAS1 PIAS2 RAB14 RAB39B RAB3IP RAB4A RAB5A TRIM23 TXNDC17 UTP25
Entrez ID		5867	80230
HPRD ID		01541	15282
Ensembl ID		ENSG00000168118	ENSG00000176783
Uniprot IDs		A0A024R3U9 A0A087WYT5 P20338	A8K7B1 Q96T51
PDB IDs		1YU9 1Z0K 2BMD 2BME	2YQM 2YW8
Enriched GO Terms of Interacting Partners?
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