SELENOK and KLHDC2

Number of citations of the paper that reports this interaction (PubMedID 30526872)
16

Data Source:
BioGRID (unspecified method)

		SELENOK	KLHDC2
Description		selenoprotein K	kelch domain containing 2
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GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Plasma Membrane Integral Component Of Membrane	Nucleus Nucleoplasm Nuclear Body Cul2-RING Ubiquitin Ligase Complex Nuclear Membrane
	Molecular Function	Protein Binding Identical Protein Binding	Protein Binding Ubiquitin Ligase-substrate Adaptor Activity
	Biological Process	Positive Regulation Of Defense Response To Virus By Host Calcium Ion Transport Response To Oxidative Stress Macrophage Derived Foam Cell Differentiation Protein Palmitoylation Endoplasmic Reticulum Calcium Ion Homeostasis Positive Regulation Of Interleukin-6 Production Positive Regulation Of Tumor Necrosis Factor Production Positive Regulation Of T Cell Proliferation Respiratory Burst After Phagocytosis Regulation Of Calcium-mediated Signaling Regulation Of Protein Transport Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress Positive Regulation Of Monocyte Chemotactic Protein-1 Production Positive Regulation Of T Cell Migration	Protein Ubiquitination Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Ubiquitin-dependent Protein Catabolic Process Via The C-end Degron Rule Pathway
Pathways
Drugs
Diseases
GWAS
Interacting Genes		38 interacting genes: AMIGO1 AQP6 BIK C6orf47 CLN8 CNR2 COMT CPLX4 CREB3 ERBB2 ERBB3 ERBB4 ERGIC3 FAM209A FFAR2 GLP1R GORAB GPR35 GPX8 IL10RA KLHDC2 LMNA MFSD6 MMD MRM1 MTIF3 MUC1 REEP4 RNF19B SLC10A1 SLC30A8 SLC35C2 SLC35E3 STMN4 STOM TMEM31 TMPRSS2 TMX2	9 interacting genes: ATL1 EML2 ERO1A EZH2 MIS12 SELENOK SELENOS STRN4 USP1
Entrez ID		58515	23588
HPRD ID		07448	08824
Ensembl ID		ENSG00000113811	ENSG00000165516
Uniprot IDs		Q9Y6D0	Q9Y2U9
PDB IDs		6DO3	6DO3 6DO4 6DO5
Enriched GO Terms of Interacting Partners?
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