RPRD1B and VAX1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		RPRD1B	VAX1
Description		regulation of nuclear pre-mRNA domain containing 1B	ventral anterior homeobox 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm RNA Polymerase II, Holoenzyme	Chromatin Nucleus
	Molecular Function	RNA Polymerase II Complex Binding Protein Binding Identical Protein Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific RNA Polymerase II Intronic Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Chromatin DNA Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Positive Regulation Of Cell Population Proliferation Regulation Of Cell Cycle Process MRNA 3'-end Processing Positive Regulation Of Transcription By RNA Polymerase II Dephosphorylation Of RNA Polymerase II C-terminal Domain	Negative Regulation Of Transcription By RNA Polymerase II Neuron Migration Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Neuroblast Proliferation Axon Guidance Central Nervous System Development Brain Development Neuron Differentiation Skeletal Muscle Cell Differentiation Camera-type Eye Development Roof Of Mouth Development
Pathways		RNA polymerase II transcribes snRNA genes RNA polymerase II transcribes snRNA genes
Drugs
Diseases
GWAS			Age at first birth ( 34211149) Body mass index ( 26426971) Brain morphology (MOSTest) ( 32665545) Cleft lip with or without cleft palate ( 28054174) Nonsyndromic cleft lip ( 31609978) Nonsyndromic cleft lip with cleft palate ( 28232668) Nonsyndromic cleft lip with or without cleft palate ( 25775280) Orofacial clefts ( 20023658 28054174)
Interacting Genes		18 interacting genes: BIN3 CDCA8 DDIT4L HMG20A HOXC4 NUTF2 PFDN6 PIP4K2B PSMB1 RASSF3 SPG21 STEEP1 TERF2 TNPO2 TUBGCP4 UBE2I VAX1 VPS37C	14 interacting genes: DVL3 EAF1 ESRRG HECW1 HMBOX1 MLLT3 PICK1 POLR3C PSMB1 RCOR3 RPRD1B SDCBP2 SPANXN2 USP20
Entrez ID		58490	11023
HPRD ID		08513	16052
Ensembl ID		ENSG00000101413	ENSG00000148704
Uniprot IDs		Q9NQG5	Q5SQQ9
PDB IDs		4FLA 4FU3 4HFG 4NAD 4Q94 4Q96
Enriched GO Terms of Interacting Partners?
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