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SRPRB and CDK5RAP3
Number of citations of the paper that reports this interaction (PubMedID
16169070
)
888
Data Source:
BioGRID
(affinity chromatography technology, affinity chromatography technology)
HPRD
(two hybrid)
SRPRB
CDK5RAP3
Description
SRP receptor subunit beta
CDK5 regulatory subunit associated protein 3
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Cytoplasm
Signal Recognition Particle Receptor Complex
Endoplasmic Reticulum Membrane
Cytoplasmic Microtubule
Membrane
Integral Component Of Membrane
Nucleus
Nucleolus
Cytoplasm
Centrosome
Cytosol
Microtubule
Membrane
Protein-containing Complex
Intracellular Membrane-bounded Organelle
Molecular Function
GTP Binding
Protein Binding
Protein Kinase Binding
Cyclin Binding
Ubiquitin-like Protein Ligase Binding
Mitogen-activated Protein Kinase Binding
NF-kappaB Binding
MDM2/MDM4 Family Protein Binding
Biological Process
Protein Targeting To ER
Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity
Liver Development
Negative Regulation Of Protein Phosphorylation
Mitotic G2 DNA Damage Checkpoint Signaling
Regulation Of Mitotic Cell Cycle
Brain Development
Cell Population Proliferation
Regulation Of Phosphatase Activity
Apoptotic Nuclear Changes
Endoplasmic Reticulum Unfolded Protein Response
Positive Regulation Of Protein Ubiquitination
Negative Regulation Of NF-kappaB Transcription Factor Activity
Response To Endoplasmic Reticulum Stress
Negative Regulation Of MAP Kinase Activity
Negative Regulation Of Protein Kinase Activity By Regulation Of Protein Phosphorylation
Mitotic G2/M Transition Checkpoint
Regulation Of Neuron Differentiation
Positive Regulation Of Transcription By RNA Polymerase II
Definitive Erythrocyte Differentiation
Protein Ufmylation
Negative Regulation Of Protein Serine/threonine Kinase Activity
Positive Regulation Of Protein Localization To Nucleus
Positive Regulation Of Signal Transduction By P53 Class Mediator
Negative Regulation Of Cellular Protein Catabolic Process
Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process
Pathways
SRP-dependent cotranslational protein targeting to membrane
XBP1(S) activates chaperone genes
Drugs
Diseases
GWAS
Alcohol consumption (transferrin glycosylation) (
21665994
)
Blood protein levels (
29875488
)
Mean corpuscular hemoglobin (
29403010
32888494
)
Mean corpuscular volume (
29403010
32888494
)
Nicotine dependence symptom count (
25555482
)
Red blood cell count (
32888494
)
Adult body size (
32376654
)
Body mass index (
26426971
)
Generalized epilepsy (
22949513
)
Metabolite levels (Pyroglutamine) (
23934736
)
Interacting Genes
3 interacting genes:
CDK5RAP3
RCHY1
UBC
13 interacting genes:
CDK5R1
CREBBP
CRMP1
DISC1
ESS2
FKBP6
HSPB1
KPNA2
SRPRB
TAB1
TAX1BP3
TSPYL4
UFL1
Entrez ID
58477
80279
HPRD ID
18105
12190
Ensembl ID
ENSG00000144867
ENSG00000108465
Uniprot IDs
Q549N5
Q9Y5M8
Q96JB5
PDB IDs
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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