PYGL and HSD17B10

Number of citations of the paper that reports this interaction (PubMedID 22496890)
6

Data Source:
BioGRID (two hybrid)

		PYGL	HSD17B10
Description		glycogen phosphorylase L	hydroxysteroid 17-beta dehydrogenase 10
Image
GO Annotations	Cellular Component	Extracellular Region Cytoplasm Cytosol Secretory Granule Lumen Extracellular Exosome Ficolin-1-rich Granule Lumen	Cytoplasm Mitochondrion Mitochondrial Matrix Plasma Membrane Mitochondrial Ribonuclease P Complex Mitochondrial Nucleoid
	Molecular Function	Purine Nucleobase Binding Protein Binding ATP Binding Glucose Binding Glycogen Phosphorylase Activity AMP Binding Vitamin Binding Pyridoxal Phosphate Binding Bile Acid Binding Identical Protein Binding Linear Malto-oligosaccharide Phosphorylase Activity SHG Alpha-glucan Phosphorylase Activity	TRNA Binding RNA Binding 3-hydroxyacyl-CoA Dehydrogenase Activity Estradiol 17-beta-dehydrogenase Activity Protein Binding Cholate 7-alpha-dehydrogenase Activity Testosterone Dehydrogenase [NAD(P)] Activity 17-beta-hydroxysteroid Dehydrogenase (NAD+) Activity 3-hydroxy-2-methylbutyryl-CoA Dehydrogenase Activity Testosterone Dehydrogenase (NAD+) Activity Androstan-3-alpha,17-beta-diol Dehydrogenase Activity Chenodeoxycholate 7-alpha-dehydrogenase (NAD+) Activity Isoursodeoxycholate 7-beta-dehydrogenase (NAD+) Activity Ursodeoxycholate 7-beta-dehydrogenase (NAD+) Activity
	Biological Process	Glycogen Metabolic Process Glycogen Catabolic Process 5-phosphoribose 1-diphosphate Biosynthetic Process Response To Bacterium Glucose Homeostasis Necroptotic Process	Isoleucine Catabolic Process Lipid Metabolic Process Fatty Acid Metabolic Process Fatty Acid Beta-oxidation Bile Acid Biosynthetic Process Mitochondrion Organization C21-steroid Hormone Metabolic Process Androgen Metabolic Process Estrogen Metabolic Process Protein Homotetramerization Brexanolone Metabolic Process Mitochondrial TRNA Methylation Mitochondrial TRNA 5'-end Processing Mitochondrial TRNA 3'-end Processing
Pathways		Neutrophil degranulation Glycogen breakdown (glycogenolysis)	tRNA processing in the mitochondrion tRNA modification in the mitochondrion Branched-chain amino acid catabolism rRNA processing in the mitochondrion
Drugs			NADH 1-Azepan-1-Yl-2-Phenyl-2-(4-Thioxo-1,4-Dihydro-Pyrazolo[3,4-D]Pyrimidin-5-Yl)Ethanone Adduct Omega-3-carboxylic acids
Diseases
GWAS		Acute lymphoblastic leukemia (childhood) ( 23007406) Blood protein levels ( 30072576 29875488) Psychosis (atypical) ( 24132900) Rectal cancer ( 33632709)	Bipolar disorder ( 31043756) Body mass index ( 28892062)
Interacting Genes		7 interacting genes: BAG1 HSD17B10 HSD3B7 IDH2 POLE2 PYGB PYGM	32 interacting genes: ALDH3B1 ALDOA APP ATP5F1A CDC42 CHD3 CPS1 CS ETFDH FAF1 GLUD1 GLUL HADHA HADHB HMGCL HMGCS2 HTRA2 KDM6A MDH1 OGDH PDHB PDHX PRKN PTEN PYGL TOMM20 TOMM22 TOMM40 TRAF3IP2 TRAF5 TRAF6 UBE2D1
Entrez ID		5836	3028
HPRD ID		01987	02223
Ensembl ID		ENSG00000100504	ENSG00000072506
Uniprot IDs		P06737	A0A0S2Z410 Q99714
PDB IDs		1EM6 1EXV 1FA9 1FC0 1L5Q 1L5R 1L5S 1L7X 1XOI 2ATI 2QLL 2ZB2 3CEH 3CEJ 3CEM 3DD1 3DDS 3DDW	1F67 1SO8 1U7T 2O23
Enriched GO Terms of Interacting Partners?
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