PEX5 and ACOT2

Number of citations of the paper that reports this interaction (PubMedID 20178365)
21

Data Source:
BioGRID (unspecified method)

		PEX5	ACOT2
Description		peroxisomal biogenesis factor 5	acyl-CoA thioesterase 2
Image
GO Annotations	Cellular Component	Cytoplasm Peroxisome Peroxisomal Membrane Golgi Apparatus Cytosol Membrane Protein-containing Complex	Mitochondrion Mitochondrial Matrix Peroxisomal Matrix Cytosol
	Molecular Function	Peroxisome Targeting Sequence Binding Peroxisome Matrix Targeting Signal-1 Binding Protein Binding Enzyme Binding Small GTPase Binding Peroxisome Membrane Targeting Sequence Binding Protein N-terminus Binding Protein Sequestering Activity	Protein Binding Palmitoyl-CoA Hydrolase Activity Acyl-CoA Hydrolase Activity Carboxylic Ester Hydrolase Activity Myristoyl-CoA Hydrolase Activity
	Biological Process	Protein Import Into Peroxisome Matrix Protein Import Into Peroxisome Matrix, Docking Negative Regulation Of Protein-containing Complex Assembly Protein Import Into Peroxisome Membrane	Very Long-chain Fatty Acid Metabolic Process Long-chain Fatty Acid Metabolic Process Fatty Acid Metabolic Process Acyl-CoA Metabolic Process
Pathways		Pexophagy	Mitochondrial Fatty Acid Beta-Oxidation Peroxisomal protein import Peroxisomal protein import
Drugs
Diseases
GWAS		IgG glycosylation ( 23382691) Night sleep phenotypes ( 27126917) Refractive error ( 32231278)	Urinary metabolite levels in chronic kidney disease ( 31959995)
Interacting Genes		77 interacting genes: ACD ACOT2 ACOT4 ACOT8 ACOX2 ACOX3 AGXT AMACR ANKRD50 ATM BAAT BRCA1 CAPRIN2 CCDC14 CROT DAO DDO DECR2 DHRS4 ECI2 EP400P1 EPHX2 GDPD5 GLMN GNPAT GSTK1 HACL1 HAO1 HAO2 HMGCL HNRNPH1 HOXA7 HSPA1A IDE IDH1 LDHB LONP2 MKRN3 MLYCD MPV17 NOS2 NUDT19 NUDT3 NUDT7 NUFIP2 PAOX PDZK1 PEX1 PEX10 PEX12 PEX13 PEX14 PEX26 PEX6 PEX7 PIPOX POT1 PRDX5 PRR13 PSAP RPL14 S100A6 SCARB1 SCP2 SCRN2 SIRT3 SLC27A2 SNUPN SSTR5 TIMMDC1 TINF2 TM6SF1 TOMM7 USP2 USP9X ZFAND3 ZNF772	3 interacting genes: INTS4 PEX5 SLC13A1
Entrez ID		5830	10965
HPRD ID		02684	10173
Ensembl ID		ENSG00000139197	ENSG00000119673
Uniprot IDs		A0A0S2Z480 A0A0S2Z4F3 A0A0S2Z4H1 B4DR50 B4E0T2 P50542	P49753
PDB IDs		1FCH 2C0L 2C0M 2J9Q 2W84 3R9A 4BXU 4KXK 4KYO	3HLK
Enriched GO Terms of Interacting Partners?
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