PVR and SLC41A2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		PVR	SLC41A2
Description		PVR cell adhesion molecule	solute carrier family 41 member 2
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Space Cytoplasm Plasma Membrane Adherens Junction Focal Adhesion Cell Surface Integral Component Of Membrane	Plasma Membrane Integral Component Of Membrane
	Molecular Function	Virus Receptor Activity Protein Binding Signaling Receptor Activity Cell Adhesion Molecule Binding	Protein Binding Magnesium Ion Transmembrane Transporter Activity
	Biological Process	Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Directed Against Tumor Cell Target Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Susceptibility To Natural Killer Cell Mediated Cytotoxicity Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Viral Entry Into Host Cell Susceptibility To T Cell Mediated Cytotoxicity	Magnesium Ion Transmembrane Transport
Pathways		Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Nectin/Necl trans heterodimerization	Metal ion SLC transporters
Drugs		Sphingosine Myristic acid
Diseases
GWAS		Alzheimer's disease ( 24755620) Alzheimer's disease or family history of Alzheimer's disease ( 30617256) Alzheimer's disease or HDL levels (pleiotropy) ( 30805717) Body mass index ( 26426971) Body mass index (age>50) ( 26426971) Body mass index x age interaction ( 26426971) Body mass index x sex x age interaction (4df test) ( 26426971) Mean platelet volume ( 32888494 27863252) Multiple sclerosis ( 21833088) Multiple sclerosis and HDL levels (pleiotropy) ( 26920376) Platelet distribution width ( 32888494)	Beta blocker survival benefit in heart failure with reduced ejection fraction (time to all cause mortality x beta blocker interaction) ( 33012170) glucocorticoid receptor gene expression in B-cell precursor acute lymphoblastic leukaemia ( 33002292)
Interacting Genes		77 interacting genes: ADIPOQ ANKRD46 AP1M2 AQP10 BRICD5 C3orf52 CD226 CD47 CD96 CLDN19 CTXN3 CYB561A3 CYHR1 CYSRT1 DMPK DYNLT1 DYNLT3 EBP EDDM3B GMEB2 GPRC5D HHATL HOXA1 INSIG2 KRTAP1-1 KRTAP1-3 KRTAP10-3 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP3-1 KRTAP3-3 KRTAP6-3 KRTAP9-3 MFSD11 NBPF19 NECTIN1 NECTIN2 NECTIN3 NINJ1 NINJ2 NOTCH2NLA OLFM4 PGA4 PLA2G3 PLAT PLP2 PLPP6 PSG11 PSG9 PSMD8 RUSF1 SCD SFTPC SLC22A4 SLC30A2 SLC35B4 SLC41A2 SMIM1 SNAP47 SYS1 TAS2R19 TIGIT TM6SF2 TMBIM6 TMEM147 TMEM229B TMEM54 TMEM65 TMEM79 TSPO VAMP5 VTN WNK1 ZDHHC15 ZDHHC22 ZFPL1	32 interacting genes: AQP6 CD79A CKAP4 CLN5 CREB3 EBP ERGIC3 ERVFRD-1 FATE1 FNDC9 FUT3 GJA5 GJB5 GPR151 GPR42 GPX8 IGFBP5 IL27RA KASH5 KIR3DL3 LDLRAD1 LEUTX LIME1 LMNA LY6G6C LYVE1 MFF PDCD1LG2 PVR SHISAL1 SSMEM1 TMEM237
Entrez ID		5817	84102
HPRD ID		01434	15389
Ensembl ID		ENSG00000073008	ENSG00000136052
Uniprot IDs		A0A0A0MSA9 A0A0C4DG49 A8K4I1 P15151	Q96JW4
PDB IDs		1DGI 1NN8 3EPC 3EPD 3EPF 3J8F 3J9F 3UDW 3URO 4FQP 6ARQ 6ISC 6O3O
Enriched GO Terms of Interacting Partners?
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