LSM2 and RSRC1

Number of citations of the paper that reports this interaction (PubMedID 16169070)
888

Data Source:
HPRD (two hybrid)

		LSM2	RSRC1
Description		LSM2 homolog, U6 small nuclear RNA and mRNA degradation associated	arginine and serine rich coiled-coil 1
Image			No pdb structure
GO Annotations	Cellular Component	P-body Nucleus Nucleoplasm U6 SnRNP Cytoplasm Cytosol U4/U6 X U5 Tri-snRNP Complex U2-type Precatalytic Spliceosome Precatalytic Spliceosome Catalytic Step 2 Spliceosome Lsm2-8 Complex Lsm1-7-Pat1 Complex	Nucleus Cytoplasm Nuclear Speck
	Molecular Function	RNA Binding Protein Binding U6 SnRNA Binding Small GTPase Binding	Protein Binding
	Biological Process	Spliceosomal Tri-snRNP Complex Assembly MRNA Splicing, Via Spliceosome MRNA Catabolic Process	Alternative MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome Protein Phosphorylation Nucleocytoplasmic Transport RNA Splicing Response To Antibiotic
Pathways		mRNA decay by 5' to 3' exoribonuclease mRNA decay by 5' to 3' exoribonuclease mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway
Drugs
Diseases
GWAS		Asthma ( 31619474) Asthma (childhood onset) ( 31619474) Asthma and major depressive disorder ( 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Blood protein levels ( 28240269) Inflammatory bowel disease ( 28067908) Rosacea symptom severity ( 29771307) Ulcerative colitis ( 28067908)	Adult body size ( 32376654) Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Body mass index ( 26426971) Chin dimples ( 27182965) Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143) Depression ( 29700475) Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Diastolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858) FEV1 ( 30804560) Height ( 23563607) Left-handedness ( 32989287) Lung function (FVC) ( 30804560) Lung function in heavy smokers (high FEV1 vs average FEV1) ( 26423011) Major depressive disorder ( 27479909) Neuroticism ( 29255261) Sporadic neuroblastoma ( 28545128) Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Systolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858)
Interacting Genes		37 interacting genes: BANP CBX8 CRMP1 DNAAF11 DNAJA1 ERG28 EXOSC10 GBP2 KRT13 LGALS7 LGALS7B LNX1 LSM1 LSM12 LSM3 LSM5 LSM6 LSM7 LSM8 LZTS1 MAGEA3 MAGEA6 MEOX2 PATL1 PNMA1 RALA REL RSRC1 SF3B2 SMN1 SNRPD2 SNRPE TEX11 TLE5 TRIM54 ZBTB16 ZNF408	9 interacting genes: ACTR3B EEF1A1 GDF9 LEKR1 LSM2 SRPK1 SRPK2 SRRM4 UTP14A
Entrez ID		57819	51319
HPRD ID		06282	18006
Ensembl ID		ENSG00000204392	ENSG00000174891
Uniprot IDs		Q9Y333	Q96IZ7
PDB IDs		3JCR 5O9Z 6AH0 6AHD 6QW6 6QX9 7ABG
Enriched GO Terms of Interacting Partners?
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