CIP2A and UBR5

Number of citations of the paper that reports this interaction (PubMedID 34145035)
0

Data Source:
BioGRID (two hybrid)

		CIP2A	UBR5
Description		cellular inhibitor of PP2A	ubiquitin protein ligase E3 component n-recognin 5
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GO Annotations	Cellular Component	Cytoplasm Cytosol Plasma Membrane Integral Component Of Membrane	Nucleus Nucleoplasm Cytosol Membrane Protein-containing Complex Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding Protein Homodimerization Activity Cadherin Binding	RNA Binding Protein Binding Zinc Ion Binding Ubiquitin-ubiquitin Ligase Activity Ubiquitin Binding Ubiquitin Protein Ligase Activity
	Biological Process		Protein Polyubiquitination DNA Repair Cellular Response To DNA Damage Stimulus Positive Regulation Of Gene Expression Positive Regulation Of Protein Import Into Nucleus Progesterone Receptor Signaling Pathway Protein K48-linked Ubiquitination Positive Regulation Of Canonical Wnt Signaling Pathway Negative Regulation Of Histone H2A K63-linked Ubiquitination Regulation Of Double-strand Break Repair Negative Regulation Of Double-strand Break Repair
Pathways
Drugs
Diseases
GWAS			Chromosomal aberration frequency (total) ( 31586183) Lymphocyte percentage of white cells ( 32888494) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Rate of cognitive decline in mild cognitive impairment (time interaction) ( 22833209) Type 2 diabetes (age of onset) ( 28060188)
Interacting Genes		11 interacting genes: ATIC CSNK2B GOLGA4 LAMB2 MYC PIK3R1 STUB1 SYNCRIP TOPBP1 UBR5 WWC3	32 interacting genes: BARD1 CIB1 CIP2A CSPP1 DYRK2 ERG GSK3B KPNA1 KPNA2 KPNB1 MAPK1 MOAP1 MYC NR1I2 OTUD5 PAIP1 PAIP2 PCK1 PGR SATB1 SMAD2 SOX2 TCEA1 TOPBP1 TXNIP UBC UBE2A UBE2B UBE2D2 UBE2D3 UBE2L3 ZNF207
Entrez ID		57650	51366
HPRD ID		11151	06436
Ensembl ID		ENSG00000163507	ENSG00000104517
Uniprot IDs		Q8TCG1	O95071
PDB IDs		5UFL	1I2T 2QHO 3PT3
Enriched GO Terms of Interacting Partners?
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