COG6 and RAB3IL1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		COG6	RAB3IL1
Description		component of oligomeric golgi complex 6	RAB3A interacting protein like 1
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Golgi Transport Complex Trans-Golgi Network Membrane	Cytosol Golgi To Plasma Membrane Transport Vesicle
	Molecular Function	Protein Binding	Guanyl-nucleotide Exchange Factor Activity Protein Binding Identical Protein Binding
	Biological Process	Intra-Golgi Vesicle-mediated Transport Protein Transport Glycosylation	Exocytosis Protein Transport Regulation Of Catalytic Activity
Pathways		COPI-mediated anterograde transport Intra-Golgi traffic Retrograde transport at the Trans-Golgi-Network	RAB GEFs exchange GTP for GDP on RABs
Drugs
Diseases
GWAS		Asthma ( 31959851 30929738 32296059) Asthma (adult onset) ( 30929738) Eosinophil counts ( 32888494 27863252) Eosinophil percentage of granulocytes ( 27863252) Eosinophil percentage of white cells ( 32888494 27863252) Height ( 31562340) Juvenile idiopathic arthritis (oligoarticular or rheumatoid factor-negative polyarticular) ( 23603761) Menarche (age at onset) ( 25231870) Multiple sclerosis ( 31604244 24076602) Neutrophil percentage of granulocytes ( 27863252) Peripheral arterial disease (traffic-related air pollution interaction) ( 27082954) Psoriasis ( 25903422 18369459) Rheumatoid arthritis ( 30423114 24390342) Rheumatoid arthritis (ACPA-positive) ( 23143596 24532676) Sum eosinophil basophil counts ( 27863252) Systemic lupus erythematosus or rheumatoid arthritis ( 27193031)	Aspartate aminotransferase levels ( 33547301) Metabolite levels ( 23823483) Oleic acid (18:1n-9) levels ( 23362303) Plasma omega-3 polyunsaturated fatty acid level (eicosapentaenoic acid) ( 21829377) Plasma omega-3 polyunsaturated fatty acid levels (alphalinolenic acid) ( 21829377) Plasma omega-3 polyunsaturated fatty acid levels (docosapentaenoic acid) ( 21829377) Plasma omega-6 polyunsaturated fatty acid levels (adrenic acid) ( 24823311) Plasma omega-6 polyunsaturated fatty acid levels (arachidonic acid) ( 24823311) Plasma omega-6 polyunsaturated fatty acid levels (dihomo-gamma-linolenic acid) ( 24823311) Plasma omega-6 polyunsaturated fatty acid levels (gamma-linolenic acid) ( 24823311) Red blood cell fatty acid levels ( 25500335) Reticulocyte fraction of red cells ( 32888494)
Interacting Genes		68 interacting genes: ARHGEF5 ATXN7 BAIAP2 BCL10 CCDC116 CCDC120 CCDC187 CCDC92 CCHCR1 CNN1 CNNM3 CSRP2 CUL5 DNM2 DOCK8 DTNB FAM110A FAM90A1 FANCG FNDC11 GAS8 GEM GOLGA2 GRAP2 IGFN1 KANK2 LGALS14 LMO4 MCM7 MFAP1 MRI1 NDUFA5 NEK6 NTAQ1 NUP58 OAS1 PLEKHA2 POM121 PPP1R18 PPP1R32 PSMA1 PSMB1 QARS1 RAB3IL1 RAB6B RSPH14 RTP5 RUNX1T1 SCNM1 SMARCD1 SNAI1 SNAP29 SNRPB SPG21 SYCP2L SYT17 TBC1D22B TMSB4X TSC1 TSGA10 TSHZ3 TSNAX TTC7B UFSP1 WASHC3 ZBTB16 ZFC3H1 ZNF417	28 interacting genes: C14orf119 C2orf68 CCDC57 COG6 CTDSP1 CYSRT1 EXOC8 FADS2 FHL5 HSF2BP IP6K1 KRT34 KRT40 KRTAP6-3 MAP3K1 MTUS2 NBPF19 NOTCH2NLA NUDT18 PSMA3 RAB11A RAB3A RAB3IP RAB8A SATB2 STX1A TIGD7 TTC7B
Entrez ID		57511	5866
HPRD ID		08445	10181
Ensembl ID		ENSG00000133103	ENSG00000167994
Uniprot IDs		A0A024RDW5 A0A140VJG7 Q9Y2V7	Q8TBN0
PDB IDs			4LI0
Enriched GO Terms of Interacting Partners?
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