ADGRB1 and PHYHIP

Number of citations of the paper that reports this interaction (PubMedID 11245925)
18

Data Source:
HPRD (in vivo, in vitro, two hybrid)

		ADGRB1	PHYHIP
Description		adhesion G protein-coupled receptor B1	phytanoyl-CoA 2-hydroxylase interacting protein
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Phagocytic Cup Extracellular Space Plasma Membrane Integral Component Of Plasma Membrane Cell-cell Junction Focal Adhesion Postsynaptic Density Integral Component Of Membrane Dendrite Dendritic Spine Perinuclear Region Of Cytoplasm	Cytoplasm
	Molecular Function	Lipopolysaccharide Binding Phosphatidylserine Binding G Protein-coupled Receptor Activity Protein Binding PDZ Domain Binding	Protein Tyrosine Kinase Binding
	Biological Process	Phagocytosis, Recognition Cell Adhesion Signal Transduction Cell Surface Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Axonogenesis Peripheral Nervous System Development Muscle Organ Development Negative Regulation Of Cell Population Proliferation Negative Regulation Of Endothelial Cell Migration Negative Regulation Of Angiogenesis Negative Regulation Of Protein Ubiquitination Negative Regulation Of Protein Catabolic Process Apoptotic Cell Clearance Engulfment Of Apoptotic Cell Innate Immune Response Regulation Of Synaptic Plasticity Defense Response To Gram-negative Bacterium Positive Regulation Of Synapse Assembly Positive Regulation Of Myoblast Fusion Positive Regulation Of Reactive Oxygen Species Biosynthetic Process	Protein Localization
Pathways
Drugs
Diseases
GWAS		Bipolar disorder x sex interaction ( 34099189)	Hypertriglyceridemia ( 23505323)
Interacting Genes		21 interacting genes: BAIAP2 BAIAP3 DLG1 DLG4 DRD2 ELMO1 ERBB2 GPR35 GPR37 LIN7A LRRC7 MAGI1 MAGI2 MAGI3 PATJ PDZD2 PHYHIP SNTA1 SNTB1 SNTB2 SNTG2	24 interacting genes: ADGRB1 COPS6 DYRK1A EEF1A1 ERG28 FAM131A HDAC11 HNRNPA1 MAGED4B MED8 METTL18 NDRG1 NDUFV3 NFE2 PHYH PNPLA2 PPIE PRMT5 S100A13 SMARCC2 SUPT5H TTR WDR89 ZZEF1
Entrez ID		575	9796
HPRD ID		04062	16345
Ensembl ID		ENSG00000181790	ENSG00000168490
Uniprot IDs		O14514	Q92561
PDB IDs
Enriched GO Terms of Interacting Partners?
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