ARID1B and CUL2

Number of citations of the paper that reports this interaction (PubMedID 20086098)
52

Data Source:
BioGRID (pull down)

		ARID1B	CUL2
Description		AT-rich interaction domain 1B	cullin 2
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GO Annotations	Cellular Component	Nucleoplasm Cytosol Plasma Membrane SWI/SNF Complex Brahma Complex NBAF Complex	Nucleoplasm Nucleolus Cytosol SCF Ubiquitin Ligase Complex VCB Complex Cullin-RING Ubiquitin Ligase Complex Cul2-RING Ubiquitin Ligase Complex
	Molecular Function	DNA Binding Transcription Coactivator Activity Protein Binding Nucleosome Binding	Ubiquitin-protein Transferase Activity Protein Binding Ubiquitin Protein Ligase Binding Protein-containing Complex Binding
	Biological Process	Chromatin Remodeling Regulation Of Transcription By RNA Polymerase II Nervous System Development Positive Regulation Of Transcription, DNA-templated Chromatin-mediated Maintenance Of Transcription	G1/S Transition Of Mitotic Cell Cycle Protein Ubiquitination SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Intrinsic Apoptotic Signaling Pathway
Pathways		RMTs methylate histone arginines RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known	Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha Neddylation Regulation of expression of SLITs and ROBOs Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29083406) Alzheimer's disease biomarkers ( 23419831) Calcium levels ( 24068962) Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Heel bone mineral density ( 30598549) Hematocrit ( 32888494) Hemoglobin levels ( 32327693) Iris color (b* coordinate) ( 30895295) Lipoprotein (a) levels ( 26377243) Low density lipoprotein cholesterol levels ( 30498476) Multiple system atrophy (pathologically confirmed) ( 27629089) Pancreatic cancer ( 22158540) Psychosis proneness (perceptual aberration scale and revised physical anhedonia scale) ( 28525603) Pulse pressure ( 27841878) Red blood cell count ( 32888494) Sensory disturbances after bilateral sagittal split ramus osteotomy ( 23834954) Type 2 diabetes ( 29621232) Vein graft stenosis in coronary artery bypass grafting ( 25881214) Western dietary pattern ( 28644415)	Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908)
Interacting Genes		15 interacting genes: ARMT1 CUL2 ENO1 GINM1 H2BC21 MAU2 MTHFD1L NCOA6 PLEKHG1 PYGM SMAD9 SMARCA2 SMARCA4 TNFRSF19 ZBTB2	35 interacting genes: ABI1 ARID1B CAND1 CCND1 CDC34 CHD3 COMMD1 COPS5 CREM DCUN1D2 DCUN1D3 DCUN1D4 DCUN1D5 E2F1 ELOC FNIP1 FZD8 GJD4 GPS1 HSD17B7P2 KAT2A KHNYN MKNK2 NEDD8 RBX1 RNF7 SAP130 SENP8 UBC UBE2D1 UBE2D3 VHL ZER1 ZNF25 ZYG11B
Entrez ID		57492	8453
HPRD ID		10660	06786
Ensembl ID		ENSG00000049618	ENSG00000108094
Uniprot IDs		Q8NFD5	A0A0A0MTN0 A0A140VKB1 B7Z1Y1 Q13617
PDB IDs		2CXY 2EH9	4WQO 5N4W 6R6H 6R7F 6R7H 6R7I 6R7N
Enriched GO Terms of Interacting Partners?
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