PTGFR and PTGER2

Number of citations of the paper that reports this interaction (PubMedID 8163486)
34

Data Source:
HPRD (in vivo)

		PTGFR	PTGER2
Description		prostaglandin F receptor	prostaglandin E receptor 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Cytoplasm Plasma Membrane Integral Component Of Plasma Membrane	Plasma Membrane Integral Component Of Plasma Membrane
	Molecular Function	Prostaglandin F Receptor Activity	Prostaglandin E Receptor Activity
	Biological Process	Inflammatory Response G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Parturition Positive Regulation Of Cell Population Proliferation Positive Regulation Of Gene Expression Response To Estradiol Response To Lipopolysaccharide Calcium-mediated Signaling Using Intracellular Calcium Source Negative Regulation Of Apoptotic Process Cellular Response To Prostaglandin D Stimulus	Inflammatory Response G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Cellular Response To Prostaglandin E Stimulus Positive Regulation Of Gastric Mucosal Blood Circulation
Pathways		Prostanoid ligand receptors G alpha (q) signalling events	Prostanoid ligand receptors G alpha (s) signalling events ADORA2B mediated anti-inflammatory cytokines production
Drugs		Travoprost Latanoprost Bimatoprost Dinoprost tromethamine Tafluprost Latanoprostene bunod	Alprostadil Dinoprostone Misoprostol Gemeprost Limaprost
Diseases
GWAS		Bipolar disorder ( 22182935) Depression in multiple sclerosis (post-diagnosis) ( 33296963) Lung cancer ( 28604730) Lung cancer in ever smokers ( 28604730) Lung function in never smokers (high FEV1 vs average FEV1) ( 26423011) Skin fluorescence in type 1 diabetes ( 27207532) Systolic blood pressure (alcohol consumption interaction) ( 24376456)
Interacting Genes		12 interacting genes: AGTR1 CTH FPGT GTPBP4 IKBKE NOC2L PHOX2B PTGDS PTGER1 PTGER2 PTGES2 PTPRT	3 interacting genes: PTGDS PTGES PTGFR
Entrez ID		5737	5732
HPRD ID		08988	08905
Ensembl ID		ENSG00000122420	ENSG00000125384
Uniprot IDs		P43088	P43116
PDB IDs
Enriched GO Terms of Interacting Partners?
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