RPGRIP1 and AEN

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid)

		RPGRIP1	AEN
Description		RPGR interacting protein 1	apoptosis enhancing nuclease
Image			No pdb structure
GO Annotations	Cellular Component	Axoneme Photoreceptor Connecting Cilium Ciliary Transition Zone Photoreceptor Distal Connecting Cilium	Nucleus Nucleoplasm Nucleolus Nuclear Membrane
	Molecular Function	Protein Binding	Nucleic Acid Binding Exonuclease Activity Protein Binding
	Biological Process	Visual Perception Retinal Rod Cell Development Response To Stimulus Neural Precursor Cell Proliferation Non-motile Cilium Assembly	Response To Ionizing Radiation Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Nucleic Acid Phosphodiester Bond Hydrolysis
Pathways
Drugs
Diseases
GWAS		Body mass index ( 26426971) Body mass index (age>50) ( 26426971) Body mass index x sex x age interaction (4df test) ( 26426971) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Height ( 31562340) Refractive error ( 32231278) Superior temporal sulcus banks volume ( 31530798)	Dupuytren's disease ( 28886342) Night sleep phenotypes ( 27126917)
Interacting Genes		26 interacting genes: AEN BRCA1 CBX8 CCDC146 CHCHD3 CSPP1 DPPA4 FAM74A4 FEM1C GATAD2B HEYL IQCE MAGEB2 NPHP4 PTF1A RNF6 RPGR RPP25L SCNM1 TBC1D7 TFPT TRIB3 ZNF337 ZNF417 ZNF564 ZNF688	38 interacting genes: AAMP CRTC3 EMD EXOSC8 GNPTAB HAP1 HOMEZ IKZF1 KANK2 KHDRBS2 KRT40 KRTAP10-1 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 LZTS2 MBNL1 MID2 MTUS2 NKX3-1 PDE4DIP PHC2 RALYL RBMY1A1 RBMY1F RPGRIP1 SPOP SSX2IP TLE5 TRIM27 TRIM41 ZBTB43 ZBTB8A ZFP64 ZNF317 ZNF408 ZNF473
Entrez ID		57096	64782
HPRD ID		05673	08573
Ensembl ID		ENSG00000092200	ENSG00000181026
Uniprot IDs		Q96KN7	Q8WTP8
PDB IDs		4QAM
Enriched GO Terms of Interacting Partners?
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