PSG5 and NLGN3

Number of citations of the paper that reports this interaction (PubMedID 25464930)
6

Data Source:
BioGRID (two hybrid)

		PSG5	NLGN3
Description		pregnancy specific beta-1-glycoprotein 5	neuroligin 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region	Plasma Membrane Integral Component Of Plasma Membrane Cell Surface Endocytic Vesicle Synapse Excitatory Synapse Spanning Component Of Membrane Presynapse Symmetric, GABA-ergic, Inhibitory Synapse Asymmetric, Glutamatergic, Excitatory Synapse Integral Component Of Postsynaptic Membrane Integral Component Of Postsynaptic Specialization Membrane
	Molecular Function	Protein Binding	Protein Binding Signaling Receptor Activity Neurexin Family Protein Binding Cell Adhesion Molecule Binding Scaffold Protein Binding
	Biological Process	Female Pregnancy	Regulation Of Respiratory Gaseous Exchange By Nervous System Process Receptor-mediated Endocytosis Neuron Cell-cell Adhesion Chemical Synaptic Transmission Synapse Assembly Learning Adult Behavior Social Behavior Synaptic Vesicle Endocytosis Axon Extension Modulation Of Chemical Synaptic Transmission Synapse Organization Positive Regulation Of Synapse Assembly Positive Regulation Of Synaptic Transmission, Glutamatergic Rhythmic Synaptic Transmission Inhibitory Postsynaptic Potential Vocalization Behavior Postsynaptic Membrane Assembly Presynaptic Membrane Assembly Presynapse Assembly Positive Regulation Of Excitatory Postsynaptic Potential Positive Regulation Of AMPA Receptor Activity
Pathways		Cell surface interactions at the vascular wall	Neurexins and neuroligins Neurexins and neuroligins
Drugs		Alitretinoin
Diseases
GWAS		Cerebral microbleeds (lobar) ( 32913026)	Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Prostate cancer ( 25217961)
Interacting Genes		4 interacting genes: NLGN3 PRPF40A PSMD8 TIE1	66 interacting genes: AKT1 ALPP AP2A2 APC2 ATF4 ATXN1 C1orf122 C1QA CCAR2 CGB3 COBL CTSD DLG2 DLG3 DLG4 DPEP2 EBPL EFEMP1 EFS FANCG FBLN1 FHOD1 FKBP1A FLNA GDF15 GUK1 HID1 HIVEP1 ITPRIP LGALS1 MAN2C1 MAP1S MEOX2 MIEN1 NFATC4 NRDC NRXN1 NRXN2 NRXN3 OAZ1 OR1F12 PDZD11 PICK1 PKIB PLB1 PLCB4 PRDX2 PSAP PSG1 PSG11 PSG3 PSG4 PSG5 QARS1 RBFOX2 SPAG5 SPINT1 SSR4 TDRD7 TLE5 TNNT3 TRIM33 TXNIP UBQLN1 UBXN6 UQCRC1
Entrez ID		5673	54413
HPRD ID		08894	02275
Ensembl ID		ENSG00000204941	ENSG00000196338
Uniprot IDs		A0A024R0S1 Q15238	B7Z3P8 Q4G160 Q6MZK0 Q9NZ94 X5D2P6 X5D7L6 X5DNV3
PDB IDs
Enriched GO Terms of Interacting Partners?
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