RNF20 and RNF40

Number of citations of the paper that reports this interaction (PubMedID 30649429)
3

Data Source:
BioGRID (pull down)

		RNF20	RNF40
Description		ring finger protein 20	ring finger protein 40
Image			No pdb structure
GO Annotations	Cellular Component	Ubiquitin Ligase Complex Nucleus Nucleoplasm Nucleolus HULC Complex	Ubiquitin Ligase Complex Nucleus Nucleoplasm Cytosol Membrane Extrinsic Component Of Membrane HULC Complex Neuron Projection Axon Terminus
	Molecular Function	P53 Binding Chromatin Binding Transcription Coactivator Activity MRNA 3'-UTR Binding Ubiquitin-protein Transferase Activity Protein Binding Ubiquitin Protein Ligase Binding Histone Binding Identical Protein Binding Metal Ion Binding	MRNA 3'-UTR Binding Ubiquitin-protein Transferase Activity Protein Binding Syntaxin-1 Binding Ubiquitin Conjugating Enzyme Binding Ubiquitin Protein Ligase Binding Protein Homodimerization Activity Protein-containing Complex Binding Metal Ion Binding
	Biological Process	Protein Polyubiquitination Regulation Of Transcription, DNA-templated Ubiquitin-dependent Protein Catabolic Process Regulation Of Mitotic Cell Cycle Histone Monoubiquitination Negative Regulation Of Cell Migration Positive Regulation Of Histone Methylation Histone H2B Ubiquitination Positive Regulation Of Transcription, DNA-templated Negative Regulation Of MRNA Polyadenylation Positive Regulation Of Histone H2B Ubiquitination	Ubiquitin-dependent Protein Catabolic Process Regulation Of Mitotic Cell Cycle Histone Monoubiquitination Histone H2B Ubiquitination Response To Peptide Hormone Negative Regulation Of MRNA Polyadenylation Positive Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Protein Polyubiquitination Positive Regulation Of Histone H2B Ubiquitination
Pathways		E3 ubiquitin ligases ubiquitinate target proteins RHOBTB1 GTPase cycle	E3 ubiquitin ligases ubiquitinate target proteins
Drugs
Diseases
GWAS			Immunoglobulin light chain (AL) amyloidosis ( 28025584)
Interacting Genes		36 interacting genes: AMOTL2 ATM BAG4 C1orf109 CDC73 EEF1D FBXO7 FGFR4 H2AC18 H2AC20 H2BC21 H2BC3 H3C14 H4C14 HSF1 HTT ITSN2 KIF11 MSL1 NCBP1 PA2G4 PAF1 PRPF8 RB1CC1 RNF40 SUMO2 TACC3 TRIM14 UBE2A UBE2B UBE2D2 UBE2E1 UBE2L3 USHBP1 XRCC3 ZDHHC17	27 interacting genes: AMOTL2 ATM CCDC146 CDC73 DISC1 DUSP29 EEF1D GRIN2A ITSN1 KIF11 MEOX2 MSL1 MTNR1B NCBP1 NINL RB1 RNF20 SFR1 TRIM51 UBE2A UBE2B UBE2D2 UBE2E1 UBE2I UBE2L6 ZCCHC12 ZNF451
Entrez ID		56254	9810
HPRD ID		07410	07411
Ensembl ID		ENSG00000155827	ENSG00000103549
Uniprot IDs		Q5VTR2	A8K6K1 O75150
PDB IDs		5TRB
Enriched GO Terms of Interacting Partners?
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