PRODH and SKIV2L

		PRODH	SKIV2L
Description		proline dehydrogenase 1	Ski2 like RNA helicase
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Mitochondrion Mitochondrial Inner Membrane Mitochondrial Matrix Intracellular Membrane-bounded Organelle	Nucleus Cytosol Ski Complex
	Molecular Function	Proline Dehydrogenase Activity FAD Binding	RNA Binding RNA Helicase Activity Protein Binding ATP Binding Hydrolase Activity
	Biological Process	Proline Metabolic Process Proline Catabolic Process Intrinsic Apoptotic Signaling Pathway In Response To Oxidative Stress Proline Catabolic Process To Glutamate Positive Regulation Of Cell Death 4-hydroxyproline Catabolic Process	RNA Catabolic Process Nuclear-transcribed MRNA Catabolic Process, 3'-5' Exonucleolytic Nonsense-mediated Decay
Pathways		Proline catabolism	Association of TriC/CCT with target proteins during biosynthesis mRNA decay by 3' to 5' exoribonuclease
Drugs		Proline
Diseases
GWAS		Amino acid levels ( 26068415) Blood metabolite levels ( 24816252) Blood metabolite ratios ( 24816252) Metabolic traits ( 21886157) Metabolite levels ( 31628463) Neutrophil count ( 32888494) Plasma free amino acid levels (adjusted for one other PFAA) ( 30659259) Plasma free amino acid levels (adjusted for twenty other PFAAs) ( 30659259) Plasma free proline levels ( 30659259) Platelet count ( 32888494) Serum metabolite concentrations in chronic kidney disease ( 29545352) Serum metabolite levels ( 33031748 25569235) White blood cell count ( 32888494)	Advanced age-related macular degeneration ( 26691988) Age-related macular degeneration ( 23577725 20861866) Asthma ( 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Blood metabolite levels ( 24816252) Blood protein levels ( 29875488 28240269) Body shape index ( 34021172) Coronary artery disease ( 29212778) Disease progression in age-related macular degeneration ( 29346644) Hip circumference adjusted for BMI ( 34021172) Inflammatory bowel disease ( 28067908) Platelet count ( 32888494) Prostate cancer ( 23535732) Ulcerative colitis ( 28067908) vWF levels ( 30586737) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		7 interacting genes: GGT3P GSC2 ITM2C RANBP1 SEPTIN5 SKIV2L TBX1	15 interacting genes: CACNB3 CDK11A CDKL5 EXOSC10 EXOSC4 GALNT13 PMPCA PRKAA2 PRODH RHOU SNRPB TNRC17 TSSK2 WDR1 XRN1
Entrez ID		5625	6499
HPRD ID		08433	02724
Ensembl ID		ENSG00000100033	ENSG00000204351
Uniprot IDs		O43272	A0A1U9X8J1 Q15477
PDB IDs
Enriched GO Terms of Interacting Partners?
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