Description |
mitogen-activated protein kinase 1 |
peroxisome proliferator activated receptor gamma |
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GO Annotations |
Cellular Component |
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Molecular Function |
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Biological Process |
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Pathways |
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Drugs |
- Acetylsalicylic acid
- Minocycline
- Isoprenaline
- Arsenic trioxide
- Olomoucine
- Phosphonothreonine
- Purvalanol
- SB220025
- Seliciclib
- Perifosine
- N,N-DIMETHYL-4-(4-PHENYL-1H-PYRAZOL-3-YL)-1H-PYRROLE-2-CARBOXAMIDE
- N-BENZYL-4-[4-(3-CHLOROPHENYL)-1H-PYRAZOL-3-YL]-1H-PYRROLE-2-CARBOXAMIDE
- (S)-N-(1-(3-CHLORO-4-FLUOROPHENYL)-2-HYDROXYETHYL)-4-(4-(3-CHLOROPHENYL)-1H-PYRAZOL-3-YL)-1H-PYRROLE-2-CARBOXAMIDE
- (3R,5Z,8S,9S,11E)-8,9,16-TRIHYDROXY-14-METHOXY-3-METHYL-3,4,9,10-TETRAHYDRO-1H-2-BENZOXACYCLOTETRADECINE-1,7(8H)-DIONE
- 5-(2-PHENYLPYRAZOLO[1,5-A]PYRIDIN-3-YL)-1H-PYRAZOLO[3,4-C]PYRIDAZIN-3-AMINE
- (1aR,8S,13S,14S,15aR)-5,13,14-trihydroxy-3-methoxy-8-methyl-8,9,13,14,15,15a-hexahydro-6H-oxireno[k][2]benzoxacyclotetradecine-6,12(1aH)-dione
- [4-({5-(AMINOCARBONYL)-4-[(3-METHYLPHENYL)AMINO]PYRIMIDIN-2-YL}AMINO)PHENYL]ACETIC ACID
- 4-[4-(4-Fluorophenyl)-2-[4-[(R)-methylsulfinyl]phenyl]-1H-imidazol-5-yl]pyridine
- Turpentine
- Ulixertinib
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- alpha-Linolenic acid
- Icosapent
- Troglitazone
- Mesalazine
- Valproic acid
- Indomethacin
- Rosiglitazone
- Fenoprofen
- Nateglinide
- Sulfasalazine
- Clofazimine
- Repaglinide
- Telmisartan
- Balsalazide
- Ibuprofen
- Glipizide
- Amiodarone
- Pioglitazone
- Mitiglinide
- Bezafibrate
- Flufenamic acid
- Resveratrol
- Phthalic Acid
- Capric acid
- Doconexent
- Oleic Acid
- (S)-3-(4-(2-Carbazol-9-Yl-Ethoxy)-Phenyl)-2-Ethoxy-Propionic Acid
- 2-{5-[3-(6-BENZOYL-1-PROPYLNAPHTHALEN-2-YLOXY)PROPOXY]INDOL-1-YL}ETHANOIC ACID
- Reglitazar
- Elafibranor
- AMG-131
- CLX-0921
- Muraglitazar
- Ertiprotafib
- Ragaglitazar
- Tesaglitazar
- (2S)-3-(1-{[2-(2-CHLOROPHENYL)-5-METHYL-1,3-OXAZOL-4-YL]METHYL}-1H-INDOL-5-YL)-2-ETHOXYPROPANOIC ACID
- (9Z,11E,13S)-13-hydroxyoctadeca-9,11-dienoic acid
- 2-{5-[3-(7-PROPYL-3-TRIFLUOROMETHYLBENZO[D]ISOXAZOL-6-YLOXY)PROPOXY]INDOL-1-YL}ETHANOIC ACID
- (4S,5E,7Z,10Z,13Z,16Z,19Z)-4-hydroxydocosa-5,7,10,13,16,19-hexaenoic acid
- (5R,6E,8Z,11Z,14Z,17Z)-5-hydroxyicosa-6,8,11,14,17-pentaenoic acid
- (8E,10S,12Z)-10-hydroxy-6-oxooctadeca-8,12-dienoic acid
- (8R,9Z,12Z)-8-hydroxy-6-oxooctadeca-9,12-dienoic acid
- 9(S)-HODE
- difluoro(5-{2-[(5-octyl-1H-pyrrol-2-yl-kappaN)methylidene]-2H-pyrrol-5-yl-kappaN}pentanoato)boron
- (2S)-2-ETHOXY-3-{4-[2-(10H-PHENOXAZIN-10-YL)ETHOXY]PHENYL}PROPANOIC ACID
- 3-(5-methoxy-1H-indol-3-yl)propanoic acid
- Indeglitazar
- (2S)-2-(4-ethylphenoxy)-3-phenylpropanoic acid
- 2-chloro-5-nitro-N-phenylbenzamide
- (2S)-2-(biphenyl-4-yloxy)-3-phenylpropanoic acid
- 3-[5-(2-nitropent-1-en-1-yl)furan-2-yl]benzoic acid
- 2-[(2,4-DICHLOROBENZOYL)AMINO]-5-(PYRIMIDIN-2-YLOXY)BENZOIC ACID
- (5E,14E)-11-oxoprosta-5,9,12,14-tetraen-1-oic acid
- 3-FLUORO-N-[1-(4-FLUOROPHENYL)-3-(2-THIENYL)-1H-PYRAZOL-5-YL]BENZENESULFONAMIDE
- Triclosan
- (2S)-2-(4-chlorophenoxy)-3-phenylpropanoic acid
- Aleglitazar
- Clinofibrate
- Cannabidiol
- Lobeglitazone
- Ciglitazone
- Dexibuprofen
- Omega-3 fatty acids
- Curcumin
- Arhalofenate
- Isoflavone
- Naveglitazar
- Fenofibric acid
- Fish oil
- Medical Cannabis
- Nabiximols
- Darglitazone
- Curcumin sulfate
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Diseases |
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GWAS |
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Interacting Genes |
251 interacting genes:
AR
ARRB1
ARRB2
ATF2
ATP1A1
BANP
BCL2
BCL3
BCL6
BRAF
C1QBP
CACYBP
CAD
CALCOCO1
CAPN2
CASP8
CASP9
CAV1
CD19
CDC25C
CDX2
CEBPB
CEP55
CHN1
CITED2
CMTM3
COPS6
CREBBP
CRP
CSNK2A1
CTNND1
CTSD
CUEDC2
DAPK1
DUSP1
DUSP16
DUSP2
DUSP3
DUSP4
DUSP5
DUSP6
DUSP7
DUSP9
DYRK1B
EGFR
EGLN3
EIF4EBP1
ELK1
ELK4
ENAH
EP300
EPOR
ERF
ESR1
ESR2
ETS1
FCGR2B
FHL3
FOS
FOXO3
FRS2
FRS3
GAB1
GAB2
GABRR1
GAPDH
GATA1
GATA2
GATA4
GJA1
GMFB
GNPTAB
GORASP2
GRB10
GRB2
GSK3B
HDAC4
HDAC6
HIF1A
HNF4A
HOMEZ
HSF1
HSF4
HSP90AA1
ID2
IER3
IFI35
IFNAR1
ILF3
IQGAP1
IRS1
ITGB6
JUN
JUND
KARS1
KDR
KHDRBS1
KLF11
KRT8
KSR1
KSR2
LAMTOR3
LCK
LIFR
LIPE
LRPAP1
LRRC4
LZTS2
MAFA
MAP2K1
MAP2K2
MAP2K4
MAP2K6
MAP2K7
MAP3K1
MAP3K10
MAPK14
MAPK8
MAPKAPK5
MAPT
MBP
MCL1
MDFI
METAP2
METTL3
MITF
MKNK1
MKNK2
MSX2
MTIF3
MTPN
MYB
MYC
NCOA1
NCOA3
NDE1
NEFH
NEK2
NGFR
NKX2-1
NOXA1
NR3C1
NR4A1
NR4A2
NR5A1
NRL
NTRK3
NUP153
PAK1
PAK2
PAX5
PDE4D
PEA15
PEBP1
PKM
PLA2G4A
PLAGL2
PLAT
PLCB1
PLK3
POLR2G
PPARA
PPARG
PPP1CA
PPP1R18
PPP1R9B
PPP2CA
PPP2R5B
PPP2R5C
PRDX6
PRKCD
PRKCE
PRKCZ
PRPSAP1
PSMA1
PTPDC1
PTPN1
PTPN5
PTPN7
PTPRC
PTPRE
PTPRH
PTPRR
PXN
RAF1
RB1
REST
RET
RGS19
RNF216
RNF8
RPS6KA1
RPS6KA2
RPS6KA3
RPS6KA4
RPS6KB1
RPTOR
RUNX1
RXRA
SCNN1G
SH2D3C
SHANK3
SHC1
SLC9A1
SMAD1
SMAD2
SMAD3
SMAD4
SNCA
SNCG
SORBS3
SOS1
SOX10
SP1
SREBF1
SREBF2
STAT3
STAT5A
STAT5B
STXBP1
STYX
SUPT20H
TCF3
TFCP2
TGIF1
TH
TIAL1
TLE5
TNFRSF1A
TNFRSF25
TNFSF11
TNIP1
TNIP2
TNKS2
TOB1
TOP2A
TP53
TPR
TSC2
TTN
TXNIP
UBE3A
UBR5
UBTF
VAV1
VDR
YBX1
YBX3
ZBTB42
ZC3HC1
ZFP36
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114 interacting genes:
ADCY4
ALOX15B
ANP32A
APP
BCAS2
BRD8
CDC34
CDK5
CEP350
CNOT1
COPS5
CREBBP
DNTTIP2
EDF1
EGFR
EP300
ESRRA
FABP1
FHOD1
FOXO1
GADD45B
GADD45G
GATA5
GRIP1
HDAC1
HDAC3
HDAC4
HELZ2
HMGA1
IGFBP3
IKBKB
JAZF1
JMJD1C
JUN
JUND
KAT2A
KAT5
KCTD13
KIF11
KIF1A
KLF5
LMO4
LRIF1
MAFF
MAP2K1
MAPK1
MAPK8
MAPK9
MED1
MED24
MFHAS1
MIF4GD
MSX2
MUC1
NCOA1
NCOA2
NCOA3
NCOA4
NCOA6
NCOR1
NCOR2
NFE2L2
NFE2L3
NFKB1
NFKBIB
NR0B1
NR0B2
NR1H2
NR1H3
NR2E3
NR4A1
NR4A2
NRIP1
NSD1
PAK4
PDIA2
PHB2
PML
POU1F1
PPARGC1A
PPM1B
PRKCA
RAD54L2
RANBP9
RARA
RB1
ROBO4
RXRA
RXRB
RXRG
SERPINH1
SFPQ
SIRT1
SMARCD3
SRSF1
STAT6
STUB1
SVIL
SYT1
TFAP2A
TNP1
TRIM24
TRIP4
UBC
UBE2I
USP7
VDR
ZBTB20
ZBTB3
ZBTB5
ZBTB9
ZNF496
ZNHIT3
ZSCAN1
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Entrez ID |
5594 |
5468 |
HPRD ID |
01496 |
03288 |
Ensembl ID |
ENSG00000100030
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ENSG00000132170
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Uniprot IDs |
P28482
Q1HBJ4
Q499G7
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A0A494C1F9
D2KUA6
E9PFV2
E9PFX5
P37231
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PDB IDs |
1PME
1TVO
1WZY
2OJG
2OJI
2OJJ
2Y9Q
3D42
3D44
3I5Z
3I60
3SA0
3TEI
3W55
4FMQ
4FUX
4FUY
4FV0
4FV1
4FV2
4FV3
4FV4
4FV5
4FV6
4FV7
4FV8
4FV9
4G6N
4G6O
4H3P
4H3Q
4IZ5
4IZ7
4IZA
4N0S
4NIF
4O6E
4QP1
4QP2
4QP3
4QP4
4QP6
4QP7
4QP8
4QP9
4QPA
4QTA
4QTE
4XJ0
4ZXT
4ZZM
4ZZN
4ZZO
5AX3
5BUE
5BUI
5BUJ
5BVD
5BVE
5BVF
5K4I
5LCJ
5LCK
5NGU
5NHF
5NHH
5NHJ
5NHL
5NHO
5NHP
5NHV
5V60
5V61
5V62
5WP1
6D5Y
6DMG
6G54
6G8X
6G91
6G92
6G93
6G97
6G9A
6G9D
6G9H
6G9J
6G9K
6G9M
6G9N
6GDM
6GDQ
6GE0
6GJB
6GJD
6NBS
6OPG
6OPH
6OPI
6Q7K
6Q7S
6Q7T
6QA1
6QA3
6QA4
6QAG
6QAH
6QAL
6QAQ
6QAW
6RQ4
6SLG
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1FM6
1FM9
1I7I
1K74
1KNU
1NYX
1PRG
1RDT
1WM0
1ZEO
1ZGY
2ATH
2F4B
2FVJ
2G0G
2G0H
2GTK
2HFP
2HWQ
2HWR
2I4J
2I4P
2I4Z
2OM9
2P4Y
2POB
2PRG
2Q59
2Q5P
2Q5S
2Q61
2Q6R
2Q6S
2Q8S
2QMV
2VSR
2VST
2VV0
2VV1
2VV2
2VV3
2VV4
2XKW
2YFE
2ZK0
2ZK1
2ZK2
2ZK3
2ZK4
2ZK5
2ZK6
2ZNO
2ZVT
3ADS
3ADT
3ADU
3ADV
3ADW
3ADX
3AN3
3AN4
3B0Q
3B0R
3B1M
3B3K
3BC5
3CDP
3CDS
3CS8
3CWD
3D6D
3DZU
3DZY
3E00
3ET0
3ET3
3FEJ
3FUR
3G9E
3GBK
3H0A
3HO0
3HOD
3IA6
3K8S
3KMG
3LMP
3NOA
3OSI
3OSW
3PBA
3PO9
3PRG
3QT0
3R5N
3R8A
3R8I
3S9S
3SZ1
3T03
3TY0
3U9Q
3V9T
3V9V
3V9Y
3VJH
3VJI
3VN2
3VSO
3VSP
3WJ4
3WJ5
3WMH
3X1H
3X1I
4A4V
4A4W
4CI5
4E4K
4E4Q
4EM9
4EMA
4F9M
4FGY
4HEE
4JAZ
4JL4
4L96
4L98
4O8F
4OJ4
4PRG
4PVU
4PWL
4R06
4R2U
4R6S
4XLD
4XTA
4XUH
4XUM
4Y29
4YT1
5AZV
5DSH
5DV3
5DV6
5DV8
5DVC
5DWL
5F9B
5GTN
5GTO
5GTP
5HZC
5JI0
5LSG
5TTO
5TWO
5U5L
5UGM
5WQX
5WR0
5WR1
5Y2O
5Y2T
5YCN
5YCP
5Z5S
5Z6S
6AD9
6AN1
6AUG
6AVI
6C1I
6C5Q
6C5T
6D3E
6D8X
6D94
6DBH
6DCU
6DGL
6DGO
6DGP
6DGQ
6DGR
6DH9
6DHA
6E5A
6ENQ
6F2L
6FZF
6FZG
6FZJ
6FZP
6FZY
6ICJ
6IJR
6IJS
6ILQ
6IZM
6IZN
6JEY
6JF0
6JQ7
6K0T
6KTM
6KTN
6L89
6L8B
6MCZ
6MD0
6MD1
6MD2
6MD4
6MS7
6O67
6O68
6ONI
6ONJ
6PDZ
6QJ5
6T6B
6T9C
6TDC
6TSG
6VZL
6VZM
6VZN
6VZO
6Y3U
6ZLY
7AHJ
7AWC
7AWD
7JQG
7LOT
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Enriched GO Terms of Interacting Partners? |
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Tagcloud (Difference) ? |
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Tagcloud (Intersection) ? |
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