ANGPTL8 and RCHY1

Number of citations of the paper that reports this interaction (PubMedID 21988832)
87

Data Source:
BioGRID (two hybrid)

		ANGPTL8	RCHY1
Description		angiopoietin like 8	ring finger and CHY zinc finger domain containing 1
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region	Ubiquitin Ligase Complex Nucleus Nucleoplasm Cytoplasm Cytosol Nuclear Speck Intracellular Membrane-bounded Organelle
	Molecular Function	Hormone Activity Protein Binding	P53 Binding Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Protein Homodimerization Activity Ubiquitin Protein Ligase Activity
	Biological Process	Signal Transduction Positive Regulation Of Protein Processing Regulation Of Lipid Metabolic Process Cellular Lipid Metabolic Process Type B Pancreatic Cell Proliferation Fat Cell Differentiation Cell Maturation Regulation Of Lipoprotein Metabolic Process Triglyceride Homeostasis	Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination Positive Regulation Of Protein Ubiquitination Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Error-free Translesion Synthesis
Pathways		Assembly of active LPL and LIPC lipase complexes	Translesion Synthesis by POLH Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		HDL cholesterol ( 24097068 24507774) HDL cholesterol levels ( 28334899 26690388) Triglyceride levels ( 29403010 33339817)	Metabolite levels ( 23823483) Response to tocilizumab in rheumatoid arthritis ( 22491018)
Interacting Genes		1 interacting genes: RCHY1	75 interacting genes: ADAMTSL4 AIG1 ANGPTL8 AOX1 AR ARF4 ATN1 BIRC3 CAMK2A CAMK2G CDK9 CDKN1B CHD8 CHEK2 COPE COX6C CREB5 CYBA DAPK1 DCUN1D5 F7 FADS6 GFI1B GORAB HOXA1 HOXA2 HOXA3 HOXB1 HOXB2 HOXB5 HOXC11 HOXC4 HOXD10 HRG KAT5 KLHL41 KRTAP9-2 LIMS2 MDM2 MEOX2 MSH3 MT2A NKD2 NLK NOTCH2NLA PGLS PLAGL2 PMM1 PRDX4 RAB11A RBM38 RILP RPLP1 RPN2 SEMA4C SERPINA1 SERPINA5 SERTAD1 SRPRB TAOK2 TMBIM1 TMEM14C TMEM184A TP53 TP63 TP73 TRIM8 UBASH3B UBC UBE2D1 UBE2D2 UBE2D3 UBE2D4 WDR74 ZNF160
Entrez ID		55908	25898
HPRD ID		14245	07607
Ensembl ID		ENSG00000130173	ENSG00000163743
Uniprot IDs		Q6UXH0	Q96PM5
PDB IDs			2JRJ 2K2C 2K2D
Enriched GO Terms of Interacting Partners?
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