LUC7L and SRSF6

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		LUC7L	SRSF6
Description		LUC7 like	serine and arginine rich splicing factor 6
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	U1 SnRNP U2-type Prespliceosome	Nucleoplasm Nuclear Speck
	Molecular Function	MRNA Binding Protein Binding Identical Protein Binding	RNA Binding MRNA Binding Protein Binding Pre-mRNA Binding
	Biological Process	MRNA Splice Site Selection	Alternative MRNA Splicing, Via Spliceosome Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome MRNA Splice Site Selection Regulation Of Keratinocyte Proliferation Response To Insulin Negative Regulation Of Keratinocyte Differentiation Negative Regulation Of MRNA Splicing, Via Spliceosome Positive Regulation Of Epithelial Cell Proliferation Involved In Lung Morphogenesis Negative Regulation Of Cell Death Regulation Of Wound Healing Negative Regulation Of Type B Pancreatic Cell Apoptotic Process
Pathways			Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination
Drugs
Diseases
GWAS		Heel bone mineral density ( 30598549) Hemoglobin concentration ( 27863252) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Mean corpuscular hemoglobin ( 32888494 28453575 20139978 27863252) Mean corpuscular hemoglobin concentration ( 32888494 27863252) Mean corpuscular volume ( 32888494 27863252) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Red blood cell count ( 32888494) Red cell distribution width ( 32888494 27863252 28957414) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494)	Adult body size ( 32376654) Antibody level in response to infection ( 25758998) Daytime sleep phenotypes ( 27126917) HDL cholesterol levels in HIV infection ( 33109212)
Interacting Genes		13 interacting genes: ANTKMT APPL1 CALM1 CHERP CTNNBL1 FBXO25 GADD45G PRDX1 PRMT5 SRSF6 SRSF7 TCERG1 TSC1	16 interacting genes: APP CLK1 LUC7L LUC7L2 OGT PPARGC1A RBM10 RNPS1 SF3B4 SREK1 SRPK1 SRPK2 SRSF4 TERF1 TERF2 TOE1
Entrez ID		55692	6431
HPRD ID		08476	09054
Ensembl ID		ENSG00000007392	ENSG00000124193
Uniprot IDs		A8MYV2 D3DU41 Q1W6G4 Q9NQ29	Q13247
PDB IDs
Enriched GO Terms of Interacting Partners?
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