HIF1AN and UACA

Number of citations of the paper that reports this interaction (PubMedID 17003112)
92

Data Source:
BioGRID (two hybrid)

		HIF1AN	UACA
Description		hypoxia inducible factor 1 subunit alpha inhibitor	uveal autoantigen with coiled-coil domains and ankyrin repeats
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Perinuclear Region Of Cytoplasm	Extracellular Region Nucleus Nucleoplasm Cytosol Cytoskeleton Extracellular Exosome
	Molecular Function	Notch Binding Protein Binding Ferrous Iron Binding Zinc Ion Binding 2-oxoglutarate-dependent Dioxygenase Activity Oxygen Sensor Activity Carboxylic Acid Binding Peptidyl-histidine Dioxygenase Activity Peptidyl-asparagine 3-dioxygenase Activity Protein Homodimerization Activity NF-kappaB Binding Ankyrin Repeat Binding Hypoxia-inducible Factor-asparagine Oxygenase Activity	Molecular_function Protein Binding
	Biological Process	Peptidyl-histidine Hydroxylation Peptidyl-aspartic Acid Hydroxylation Peptidyl-asparagine Hydroxylation Positive Regulation Of Myoblast Differentiation Negative Regulation Of Notch Signaling Pathway Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Positive Regulation Of Vasculogenesis	Biological_process Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Apoptotic Signaling Pathway Negative Regulation Of NIK/NF-kappaB Signaling
Pathways		Cellular response to hypoxia	RHOH GTPase cycle Regulation of the apoptosome activity
Drugs		D-tartaric acid N-(carboxycarbonyl)-D-phenylalanine
Diseases
GWAS		Body mass index ( 28892062 25673413) Brain morphology (MOSTest) ( 32665545) Cerebrospinal fluid t-tau:AB1-42 ratio ( 30153862) Metabolite levels ( 23823483) Palmitoleic acid (16:1n-7) levels ( 28298293 23362303)	Atrial fibrillation ( 29892015) Pulmonary function ( 23932459)
Interacting Genes		19 interacting genes: ANKK1 ANKRD12 ANKRD37 ANKRD50 ASB13 ASB4 ASB7 ASB9 FBF1 HDAC1 HDAC2 HDAC3 HIF1A INVS NAA10 SIAH1 TP53BP2 UACA VHL	14 interacting genes: AHCYL1 ANKRD28 CCDC125 CELSR3 HIF1AN JPH1 KRT31 KRT40 MED14 PRKAR1B RTP2 SMAD6 STAMBP UBQLN2
Entrez ID		55662	55075
HPRD ID		09426	11657
Ensembl ID		ENSG00000166135	ENSG00000137831
Uniprot IDs		Q9NWT6	Q9BZF9
PDB IDs		1H2K 1H2L 1H2M 1H2N 1IZ3 1MZE 1MZF 1YCI 2CGN 2CGO 2ILM 2W0X 2WA3 2WA4 2XUM 2Y0I 2YC0 2YDE 3D8C 3KCX 3KCY 3OD4 3P3N 3P3P 4AI8 4B7E 4B7K 4BIO 4JAA 4NR1 4Z1V 4Z2W 5JWK 5JWL 5JWP 5OP6 5OP8 5OPC 6H9J 6HA6 6HC8 6HKP 6HL5 6HL6 6RUJ
Enriched GO Terms of Interacting Partners?
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