DNAJA4 and SH3BP4

Number of citations of the paper that reports this interaction (PubMedID 18654987)
21

Data Source:
BioGRID (two hybrid)

		DNAJA4	SH3BP4
Description		DnaJ heat shock protein family (Hsp40) member A4	SH3 domain binding protein 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Membrane	Nucleus Cytoplasm Clathrin-coated Pit Clathrin-coated Vesicle Extracellular Exosome
	Molecular Function	Protein Binding ATP Binding Hsp70 Protein Binding Metal Ion Binding Unfolded Protein Binding Chaperone Binding	GDP-dissociation Inhibitor Activity Protein Binding Small GTPase Binding Identical Protein Binding
	Biological Process	Response To Heat Negative Regulation Of Endothelial Cell Migration Positive Regulation Of Gene Expression Protein Refolding Negative Regulation Of Inclusion Body Assembly	Endocytosis Negative Regulation Of Cell Population Proliferation Positive Regulation Of Autophagy Negative Regulation Of Cell Growth Negative Regulation Of TOR Signaling Negative Regulation Of GTPase Activity Amino Acid Import Regulation Of Catalytic Activity Protein Localization To Lysosome Cellular Response To Amino Acid Stimulus
Pathways		HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand	Amino acids regulate mTORC1
Drugs
Diseases
GWAS		Eyebrow thickness ( 26926045) Hematocrit ( 32888494) Hemoglobin levels ( 32327693) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Intracranial aneurysm ( 29531279) Mean corpuscular volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Platelet count ( 32888494) Plateletcrit ( 32888494) Red cell distribution width ( 32888494 27863252 28957414) Reticulocyte count ( 32888494 27863252) Reticulocyte fraction of red cells ( 32888494 27863252) Serum metabolite levels ( 33031748)	Depression in smokers ( 30219690) Dialysis-related mortality ( 21546767) Mean corpuscular hemoglobin ( 29403010) Mean corpuscular volume ( 29403010) Obstetric antiphospholipid syndrome ( 28424481) Orofacial clefts ( 22419666) Platelet count ( 32888494) Plateletcrit ( 32888494) Schizophrenia ( 34099189) Schizophrenia x sex interaction ( 34099189) Triglyceride levels in HIV infection ( 33109212)
Interacting Genes		5 interacting genes: BANP ERG HYKK SH3BP4 WDR61	23 interacting genes: AMT C2orf73 CCT3 CEP78 CIZ1 DNAJA4 FKBP4 GAPDHS GIPC1 GKAP1 HSPA5 MPHOSPH8 MRGBP NFU1 PLEKHA1 PRR14 PSMA1 TCP1 TTC1 TXNL1 YWHAE YWHAG ZBTB37
Entrez ID		55466	23677
HPRD ID		09920	09285
Ensembl ID		ENSG00000140403	ENSG00000130147
Uniprot IDs		Q69YX3 Q8WW22	Q9P0V3
PDB IDs
Enriched GO Terms of Interacting Partners?
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