SHFL and TENM4

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		SHFL	TENM4
Description		shiftless antiviral inhibitor of ribosomal frameshifting	teneurin transmembrane protein 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	P-body Nucleus Nucleoplasm Cytoplasm Cytosol	Nucleus Cytoplasm Plasma Membrane Integral Component Of Plasma Membrane Neuron Projection
	Molecular Function	RNA Binding Protein Binding Ribosome Binding Sequence-specific MRNA Binding	Protein Binding Protein Homodimerization Activity Protein Heterodimerization Activity Cell Adhesion Molecule Binding
	Biological Process	Regulation Of Translational Termination Response To Type I Interferon Response To Interferon-gamma Response To Type III Interferon Response To Interferon-beta Negative Regulation Of Viral Genome Replication Innate Immune Response Defense Response To Virus Viral Translational Frameshifting Negative Regulation Of Translational Frameshifting	Gastrulation With Mouth Forming Second Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Signal Transduction Regulation Of Myelination Positive Regulation Of Myelination Central Nervous System Myelin Formation Neuron Development Positive Regulation Of Oligodendrocyte Differentiation Cardiac Muscle Cell Proliferation Cardiac Cell Fate Specification Positive Regulation Of Gastrulation
Pathways
Drugs
Diseases
GWAS			Attention deficit hyperactivity disorder (inattention symptoms) ( 32595297) Bipolar disorder ( 31043756) Bipolar I disorder ( 31043756) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Gut microbiota alpha diversity (PD_whole_tree index) ( 33208821) Hair greying ( 26926045) Lactate dehydrogenase levels ( 29403010) Liver enzyme levels (gamma-glutamyl transferase) ( 33972514) Lung cancer in never smokers ( 28604730) Night sleep phenotypes ( 27126917) Right lateral prefrontal cortical growth ( 29682794) Systolic blood pressure and diastolic blood pressure (bivariate analysis) ( 33539483) Tourette syndrome ( 30818990)
Interacting Genes		67 interacting genes: ADAMTSL4 CADPS CCDC136 CCNDBP1 CYSRT1 DRICH1 DTNBP1 DVL3 ECSIT FBXL12 FHL5 HSF2BP IKZF1 INCA1 KLF15 KRT31 KRT40 KRTAP1-1 KRTAP1-3 KRTAP1-5 KRTAP10-1 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP12-3 KRTAP17-1 KRTAP2-3 KRTAP2-4 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP4-4 KRTAP4-5 KRTAP5-7 KRTAP5-9 KRTAP9-2 KRTAP9-3 LNX1 LURAP1 LZTS2 MAGEA1 MDFI MEOX2 MID2 MTUS2 NBPF19 NOTCH2NLA PCSK5 PDE4DIP PICK1 PPP2R5A SPRY2 SSX2IP TCF4 TENM4 TERF1 TLE5 TNS2 TRAF1 TRIB3 TRIM42 TRIM55 TRIM63 VWC2 ZNF835	11 interacting genes: DOCK2 GAB2 HOXB9 LCE3D LGALS4 PLSCR4 RSF1 SHFL TMEM126B ZNF587 ZNF696
Entrez ID		55337	26011
HPRD ID		07747	19400
Ensembl ID		ENSG00000130813	ENSG00000149256
Uniprot IDs		Q9NUL5	Q6N022
PDB IDs
Enriched GO Terms of Interacting Partners?
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