PPP3CC and ITPKC

Number of citations of the paper that reports this interaction (PubMedID 21988832)
87

Data Source:
BioGRID (two hybrid)

		PPP3CC	ITPKC
Description		protein phosphatase 3 catalytic subunit gamma	inositol-trisphosphate 3-kinase C
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Calcineurin Complex Presynapse Glutamatergic Synapse	Nucleus Cytoplasm Cytosol Nuclear Speck
	Molecular Function	Protein Binding Calmodulin Binding Calmodulin-dependent Protein Phosphatase Activity Metal Ion Binding Protein Serine Phosphatase Activity Protein Threonine Phosphatase Activity	Inositol Hexakisphosphate Kinase Activity Calmodulin Binding ATP Binding Inositol-1,4,5-trisphosphate 3-kinase Activity Kinase Activity
	Biological Process	Protein Dephosphorylation Brain Development Calcineurin-NFAT Signaling Cascade Calcineurin-mediated Signaling Positive Regulation Of Synaptic Vesicle Endocytosis	Phosphorylation Inositol Phosphate Biosynthetic Process Phosphatidylinositol Phosphate Biosynthetic Process
Pathways		Activation of BAD and translocation to mitochondria DARPP-32 events	Synthesis of IP3 and IP4 in the cytosol
Drugs
Diseases
GWAS		General risk tolerance (MTAG) ( 30643258) HIV-1 viral setpoint ( 20205591) Verbal declarative memory ( 25648963)	Blood protein levels ( 28240269) Caffeine metabolism (plasma 1,7-dimethylxanthine (paraxanthine) level) ( 27702941) Caffeine metabolism (plasma 1,7-dimethylxanthine (paraxanthine) to 1,3,7-trimethylxanthine (caffeine) ratio) ( 27702941) Caffeine metabolism (plasma 3,7-dimethylxanthine (theobromine) level) ( 27702941) Carotid intima media thickness (mean) ( 31801372) Kawasaki disease ( 33106546 33772158 22081228)
Interacting Genes		19 interacting genes: AMPH APP BCL2 BMPR1B CABIN1 CSNK2B ENTPD4 GFRA2 HAX1 ITPKC LEPROTL1 PPP3R1 SDC2 SLC18A1 SORBS3 SPATA33 TGFBR1 THAP7 UNC119	1 interacting genes: PPP3CC
Entrez ID		5533	80271
HPRD ID		00236	09400
Ensembl ID		ENSG00000120910	ENSG00000086544
Uniprot IDs		P48454	A0A024R0N8 Q96DU7
PDB IDs			2A98
Enriched GO Terms of Interacting Partners?
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