PEF1 and SOHLH1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		PEF1	SOHLH1
Description		penta-EF-hand domain containing 1	spermatogenesis and oogenesis specific basic helix-loop-helix 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Endoplasmic Reticulum COPII Vesicle Coat Cul3-RING Ubiquitin Ligase Complex Extracellular Exosome	Chromatin Nucleus Cytoplasm
	Molecular Function	RNA Binding Calcium Ion Binding Protein Binding Identical Protein Binding Protein Heterodimerization Activity Protein Dimerization Activity Calcium-dependent Protein Binding Ubiquitin Ligase-substrate Adaptor Activity	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Protein Binding Protein Homodimerization Activity Protein Heterodimerization Activity
	Biological Process	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Neural Crest Formation Neural Crest Cell Development Protein Ubiquitination COPII Vesicle Coating Response To Calcium Ion Positive Regulation Of Protein Monoubiquitination	Regulation Of Transcription By RNA Polymerase II Spermatogenesis Oocyte Differentiation Cell Differentiation
Pathways
Drugs		Calcium citrate Calcium Phosphate Calcium phosphate dihydrate
Diseases
GWAS		Asthma ( 31959851) Body mass index ( 26426971) Cognitive ability ( 29186694) Cognitive ability (MTAG) ( 29186694) General cognitive ability ( 29844566) Hypoalbuminemia ( 34050200) Intelligence (MTAG) ( 29326435) Severe aortic features in Marfan syndrome ( 30087447)
Interacting Genes		40 interacting genes: AKAP8L ALG2 ANKRD10 BAG4 BPIFA1 C11orf1 CALCOCO2 CEP55 CTAG1A CTAG1B CUL3 DAZAP2 DMRTB1 EIF4G1 EWSR1 FAM168A FOXR2 HEMK1 HGS HYDIN INCA1 KLHL12 KRTAP12-1 KRTAP15-1 KRTAP19-1 MED25 METTL15 NR0B2 PDCD6 SEC24A SEC31A SMUG1 SOHLH1 SPAG8 SPG21 STH TFG VPS37C WWOX ZIC1	26 interacting genes: ACTN3 ARID5A C10orf55 CASP3 CERCAM CTAG1A CTAG1B DTX2 FAM222B HEMK1 IL16 KRTAP19-5 NUP54 OIP5 PEF1 PFDN5 PRKAA2 PSMB4 RUSC1 STH SUOX TENT5B TLE5 TRAF1 USHBP1 ZMYND12
Entrez ID		553115	402381
HPRD ID		10143	16678
Ensembl ID		ENSG00000162517	ENSG00000165643
Uniprot IDs		A0A384MQX5 Q9UBV8	Q5JUK2
PDB IDs
Enriched GO Terms of Interacting Partners?
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