MRGBP and TRRAP

Number of citations of the paper that reports this interaction (PubMedID 12963728)
100

Data Source:
HPRD (in vitro)

		MRGBP	TRRAP
Description		MRG domain binding protein	transformation/transcription domain associated protein
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm NuA4 Histone Acetyltransferase Complex	SAGA Complex Swr1 Complex Nucleus Nucleoplasm Golgi Apparatus Transcription Factor TFTC Complex NuA4 Histone Acetyltransferase Complex
	Molecular Function	Protein Binding	Transcription Coregulator Activity Protein Binding Kinase Activity
	Biological Process	Regulation Of Transcription By RNA Polymerase II Histone Acetylation Regulation Of Growth	DNA Repair Regulation Of Transcription, DNA-templated Histone Acetylation Histone Deubiquitination Histone H4 Acetylation Histone H2A Acetylation
Pathways		HATs acetylate histones	Formation of the beta-catenin:TCF transactivating complex Formation of the beta-catenin:TCF transactivating complex HATs acetylate histones Ub-specific processing proteases
Drugs
Diseases
GWAS			Hemoglobin levels ( 32327693) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494 27863252) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494)
Interacting Genes		25 interacting genes: ACTB ACTL6A BRD8 DAPK1 DMAP1 HSPB1 ING1 KRTAP1-1 KRTAP10-7 KRTAP17-1 KRTAP5-7 LRRK2 MEAF6 MFHAS1 MORF4L1 MORF4L2 MSL1 NBPF19 NOTCH2NLA RUVBL1 SH3BP4 TRRAP TUBB VAV2 YEATS4	19 interacting genes: ACTL6A ATXN7 AURKA BRCA1 BRD8 CDC42 CTNNB1 E2F1 E2F4 EP400 ESR1 KAT2A MAX MMS22L MRGBP MYC PYGO2 SKP1 TCF3
Entrez ID		55257	8295
HPRD ID		16646	04310
Ensembl ID		ENSG00000101189	ENSG00000196367
Uniprot IDs		Q9NV56	Q9Y4A5
PDB IDs		2N1D
Enriched GO Terms of Interacting Partners?
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