SMG8 and PDZD11

		SMG8	PDZD11
Description		SMG8 nonsense mediated mRNA decay factor	PDZ domain containing 11
Image			No pdb structure
GO Annotations	Cellular Component	Cellular_component Cytosol	Extracellular Region Cytosol Cell-cell Junction Adherens Junction Basolateral Plasma Membrane Synapse Pore Complex Presynapse
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Regulation Of Protein Kinase Activity	Neurotransmitter Secretion Maintenance Of Epithelial Cell Apical/basal Polarity Pore Complex Assembly Protein Localization To Basolateral Plasma Membrane
Pathways		Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)	Biotin transport and metabolism Vitamin B5 (pantothenate) metabolism Transport of vitamins, nucleosides, and related molecules Ion influx/efflux at host-pathogen interface Ion transport by P-type ATPases
Drugs
Diseases
GWAS
Interacting Genes		3 interacting genes: MKS1 PDZD11 SMG1	17 interacting genes: ATP2B2 ATP7A CD79B EDEM1 GDPD2 KIF4A MAGI2 MYO1F NLGN3 PLEKHA5 RAB11FIP2 SIGMAR1 SMG8 SNX12 TAF1 TEX11 ZMYM3
Entrez ID		55181	51248
HPRD ID		08551	06622
Ensembl ID		ENSG00000167447	ENSG00000120509
Uniprot IDs		Q8ND04	Q5EBL8
PDB IDs		6L54 6SYT 6Z3R
Enriched GO Terms of Interacting Partners?
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