RMDN3 and VKORC1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		RMDN3	VKORC1
Description		regulator of microtubule dynamics 3	vitamin K epoxide reductase complex subunit 1
Image
GO Annotations	Cellular Component	Nucleus Cytoplasm Mitochondrion Mitochondrial Outer Membrane Spindle Microtubule Integral Component Of Membrane Organelle Membrane Contact Site Intercellular Bridge Mitotic Spindle Pole	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane
	Molecular Function	Protein Binding Microtubule Binding	Protein Binding Vitamin-K-epoxide Reductase (warfarin-sensitive) Activity Quinone Binding
	Biological Process	Cellular Calcium Ion Homeostasis Apoptotic Process Cell Differentiation	Xenobiotic Metabolic Process Blood Coagulation Peptidyl-glutamic Acid Carboxylation Vitamin K Metabolic Process Bone Development
Pathways			Metabolism of vitamin K
Drugs			Menadione Dicoumarol Phenindione Warfarin Phenprocoumon Acenocoumarol
Diseases
GWAS		Anxiety and stress-related disorders ( 31116379) Malaria ( 31844061) Refractive error ( 32231278)	Bipolar disorder ( 31043756) Bipolar I disorder ( 31043756) Body fat distribution (arm fat ratio) ( 30664634) Warfarin maintenance dose ( 18535201 20833655 19300499 26265036) Warfarin maintenance dose (adjusted for clinical factors) ( 28686080)
Interacting Genes		25 interacting genes: CYB561D2 EGFL8 EMP3 FAM3C GIMAP1 LHFPL5 NRM PELI2 PLP1 PSEN1 SLC13A3 SLC30A8 STX2 STX3 TF TFRC TMEM100 TMEM140 TMEM147 TMEM203 TMEM243 VAMP3 VKORC1 YWHAB YWHAG	94 interacting genes: AHSG APLP2 APOA1 APOA2 APOC1 APOC3 APOC4 ARL6IP5 ASGR1 ASGR2 ATP5MC3 ATP6AP2 BCAP31 C1S CCDC12 CCDC167 CD63 CD81 CD9 CLDN10 CNN3 COMT CPLX4 CREB3 CREB3L1 CXADR DCTPP1 DPM2 ECHDC1 FAM209A FAM210B FGG FGL1 FIS1 FTL GJB1 GORAB GPR152 HAMP HDAC6 HOMER2 HP HPR HSD17B7 IFITM3 JAGN1 KCNK17 LIG4 LMNA MANBAL METTL7B MSMO1 MSRB1 MT1X MUC1 PCDH1 PCMT1 PDIA6 PIGH PLP2 PPA2 PPIB PROCR REEP5 RMDN1 RMDN3 RMND5A SAA1 SAT1 SERPINA1 SLC15A3 SLC22A2 SLC25A1 SLC31A2 SLC7A14 SNORA12 SPTSSA STAT6 SURF4 TF TMBIM4 TMEM120A TMEM134 TMEM176A TMEM230 TMEM242 TMEM256 TMEM35B TMEM45B TRAM1 TREX1 VAPB YIF1A ZCCHC24
Entrez ID		55177	79001
HPRD ID		07687	10540
Ensembl ID		ENSG00000137824	ENSG00000167397
Uniprot IDs		A0A024R9P6 Q96TC7	A0A0S2Z5X7 A0A0S2Z6I4 Q9BQB6
PDB IDs		7CC7	6WV3 6WV4 6WV5 6WV6 6WV7 6WVH
Enriched GO Terms of Interacting Partners?
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