PPP2CA and AKAP6

  • Number of citations of the paper that reports this interaction (PubMedID 11590243)
  • 55

PPP2CA

AKAP6

Description protein phosphatase 2 catalytic subunit alpha A-kinase anchoring protein 6
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Adult body size ( 32376654)
  • Age at first sexual intercourse ( 34211149)
  • Anorexia nervosa ( 21079607)
  • Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028)
  • Asthma ( 29273806)
  • Atrial fibrillation ( 30061737 29892015)
  • Bipolar disorder ( 31043756)
  • Body mass index ( 28892062 25673413 29273807 28448500)
  • Body mass index (joint analysis main effects and physical activity interaction) ( 28448500)
  • Body mass index and systole blood pressure (pairwise) ( 33619380)
  • Body mass index in physically active individuals ( 28448500)
  • Body size at age 10 ( 32376654)
  • Coffee consumption ( 31046077)
  • Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203)
  • Cognitive function ( 25644384)
  • Creatine kinase levels ( 29403010)
  • Diisocyanate-induced asthma ( 25918132)
  • Economic and political preferences (environmentalism) ( 22566634)
  • Fasting blood insulin (BMI interaction) ( 22581228)
  • General cognitive ability ( 29844566)
  • Glioma ( 28346443)
  • HDL cholesterol levels ( 32203549)
  • Intelligence (MTAG) ( 29326435)
  • Night sleep phenotypes ( 27126917)
  • Non-glioblastoma glioma ( 28346443)
  • Photic sneeze reflex ( 27182965)
  • PR interval ( 32439900)
  • Refractive error ( 32231278)
  • Schizophrenia ( 28991256 30285260)
  • Spherical equivalent or myopia (age of diagnosis) ( 29808027)
  • Type 2 diabetes ( 30297969)
  • Type 2 diabetes or prostate cancer (pleiotropy) ( 33290408)
  • Walking pace ( 33128006)
Interacting Genes 97 interacting genes: ADCY8 AKAP6 AKT1 AKT3 AMOTL2 APC AXIN1 BCL2 BEST1 BMPR1B BRAF C3orf36 CAD CAMK1 CARD11 CAV1 CCNG1 CCNG2 CDC42BPB CDK2 CDK6 CDKN2C CEBPA CHEK2 CLPP CSNK2B CXCR2 DELEC1 DVL3 EEF2 EIF4EBP1 ETF1 FCAR GABRB3 GAD1 GOLGA2 HTT IGBP1 IL3 ISYNA1 JAK2 KISS1R L3MBTL3 MAPK1 MAPK3 MAPT MID1 MRPS26 MYC MYH9 NME2 NOSIP NXN PACS1 PAK1 PIM1 PPP1CA PPP2R1A PPP2R1B PPP2R2A PPP2R3B PPP2R5B PPP2R5C PPP2R5E PRKAA1 PRKCD PTEN PTN PXN PYGM RACGAP1 RBL2 RELA RHO RHOB RORC RPS6KB1 RRAS SET SGK1 SGO1 SGO2 STAT5A STAT5B STRN TIAM1 TLX1 TP53 TRIM28 TRIM35 TRIP13 TSC2 UBAP2 VAC14 VDR XRN1 YPEL3 19 interacting genes: BIRC5 CALM1 CDC5L DISC1 DTNBP1 FUT3 GEMIN2 MAGEA6 PABPN1 PDE4D PGC PPP2CA PRKAR2A PTPRM RYR1 RYR2 SLC8A1 SPTSSA SSTR1
Entrez ID 5515 9472
HPRD ID 08912 05257
Ensembl ID ENSG00000113575 ENSG00000151320
Uniprot IDs B3KUN1 P67775 B2RP22 Q13023
PDB IDs 2IAE 2IE3 2IE4 2NPP 2NYL 2NYM 3C5W 3DW8 3FGA 3K7V 3K7W 3P71 4I5L 4I5N 4IYP 4LAC 5W0W 6NTS 7CUN
Enriched GO Terms of Interacting Partners?
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