RALGPS2 and OSBPL3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		RALGPS2	OSBPL3
Description		Ral GEF with PH domain and SH3 binding motif 2	oxysterol binding protein like 3
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Plasma Membrane	Endoplasmic Reticulum Membrane Cytosol Plasma Membrane Membrane Nuclear Membrane Filopodium Tip Intracellular Membrane-bounded Organelle Perinuclear Endoplasmic Reticulum
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity Protein Binding	Protein Binding Sterol Transporter Activity Cholesterol Binding Sterol Binding
	Biological Process	Small GTPase Mediated Signal Transduction Regulation Of Ral Protein Signal Transduction Regulation Of Catalytic Activity	Bile Acid Biosynthetic Process Sterol Transport
Pathways			Synthesis of bile acids and bile salts
Drugs
Diseases
GWAS		Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (MOSTest) ( 32665545) FEV1 ( 30804560) Lung function (FVC) ( 30804560) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Systemic lupus erythematosus ( 32771030)	Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Bipolar disorder ( 31043756) Coronary artery calcified atherosclerotic plaque score in type 2 diabetes ( 29221444) Pursuit maintenance gain ( 29064472) Sulfasalazine-induced agranulocytosis ( 28762467)
Interacting Genes		5 interacting genes: IFT20 OSBPL3 YWHAB YWHAG YWHAZ	26 interacting genes: ACSM1 BYSL FAM161A GABARAPL1 GABARAPL2 LNX1 MCRS1 PALS2 PLK4 PRPF18 PRPF3 RALGPS2 RPL11 STK35 SYTL4 TCEA2 TCEANC TRAF3IP3 WT1 YWHAB YWHAG ZBTB16 ZNF48 ZNF497 ZNF648 ZNF835
Entrez ID		55103	26031
HPRD ID		15206	09474
Ensembl ID		ENSG00000116191	ENSG00000070882
Uniprot IDs		Q86X27	Q9H4L5
PDB IDs			7CYZ
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?