TMEM51 and UBE2J1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		TMEM51	UBE2J1
Description		transmembrane protein 51	ubiquitin conjugating enzyme E2 J1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cellular_component Integral Component Of Membrane	Nucleus Endoplasmic Reticulum Membrane Integral Component Of Membrane
	Molecular Function	Molecular_function Protein Binding	Protein Binding ATP Binding Ubiquitin Protein Ligase Binding Ubiquitin Conjugating Enzyme Activity
	Biological Process	Biological_process	Protein Polyubiquitination Spermatid Development Protein N-linked Glycosylation Via Asparagine Ubiquitin-dependent ERAD Pathway Regulation Of Tumor Necrosis Factor Production Negative Regulation Of Retrograde Protein Transport, ER To Cytosol
Pathways			Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Acute ischemic stroke x type 2 diabetes interaction ( 32541925) Cocaine use disorder ( 31490055) Cocaine use disorder x non-traditional parental care interaction ( 31490055)
Interacting Genes		36 interacting genes: AQP6 BCL2L13 C14orf180 C4orf3 CCDC167 CCL4L2 CLCA4 CREB3 CYB5R3 CYP4F2 EBP GET3 LMNA MRPL12 NINJ2 PLP2 PTPN5 REEP4 RTP2 SEC61G SFT2D2 SFXN3 SMAGP SMIM1 STRIT1 TMEM107 TMEM14A TMEM14B TMEM242 TMEM254 TMIE TMX2 TSNARE1 UBE2J1 VAMP4 VTI1B	47 interacting genes: AQP2 BIRC2 BRCA1 CD79A CDS1 CLTRN CREB3 CYB561 DIO2 EBP ELOVL4 FAM209A FAM210B FCER1G GKN1 GOLT1A JAGN1 LAPTM5 LRSAM1 LY6G6C LYVE1 MAPKAPK2 MFSD14B MFSD3 MS4A6E PJA2 PLPPR2 PRKN PROKR2 REEP4 RNF2 SEC11C SLC10A6 SLC26A5 TLCD4 TM4SF18 TM4SF19 TMEM14B TMEM31 TMEM51 TMX2 TOPORS TRHR TRIM27 TRIM63 UBA1 UBC
Entrez ID		55092	51465
HPRD ID		07651	15599
Ensembl ID		ENSG00000171729	ENSG00000198833
Uniprot IDs		A0A024QZ97 Q9BSA0 Q9NW97	Q9Y385
PDB IDs
Enriched GO Terms of Interacting Partners?
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