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LAMTOR1 and EEF1A1
Number of citations of the paper that reports this interaction (PubMedID
16169070
)
888
Data Source:
BioGRID
(two hybrid)
HPRD
(two hybrid)
LAMTOR1
EEF1A1
Description
late endosomal/lysosomal adaptor, MAPK and MTOR activator 1
eukaryotic translation elongation factor 1 alpha 1
Image
GO Annotations
Cellular Component
Lysosome
Lysosomal Membrane
Plasma Membrane
Late Endosome Membrane
Azurophil Granule Membrane
Specific Granule Membrane
Membrane Raft
Extracellular Exosome
Ragulator Complex
Ficolin-1-rich Granule Membrane
Extracellular Region
Extracellular Space
Nucleus
Nucleolus
Cytoplasm
Cytosol
Eukaryotic Translation Elongation Factor 1 Complex
Plasma Membrane
Membrane
Cortical Actin Cytoskeleton
Ruffle Membrane
Secretory Granule Lumen
Extracellular Exosome
Cytoplasmic Side Of Lysosomal Membrane
Ficolin-1-rich Granule Lumen
Molecular Function
Guanyl-nucleotide Exchange Factor Activity
Protein Binding
GTPase Binding
Molecular Adaptor Activity
TRNA Binding
RNA Binding
Translation Elongation Factor Activity
GTPase Activity
Protein Binding
GTP Binding
Kinase Binding
Protein Kinase Binding
Biological Process
Regulation Of Cell Growth
Regulation Of Receptor Recycling
Endosome Organization
Lysosome Organization
Regulation Of Cholesterol Esterification
Regulation Of Cholesterol Efflux
Endosomal Transport
Positive Regulation Of TOR Signaling
Lysosome Localization
Cellular Protein Localization
Cholesterol Homeostasis
Positive Regulation Of MAPK Cascade
Regulation Of Catalytic Activity
Regulation Of Cholesterol Import
Cellular Response To Amino Acid Stimulus
Translation
Translational Elongation
Cellular Response To Epidermal Growth Factor Stimulus
Regulation Of D-erythro-sphingosine Kinase Activity
Regulation Of Chaperone-mediated Autophagy
Pathways
Macroautophagy
MTOR signalling
mTORC1-mediated signalling
Energy dependent regulation of mTOR by LKB1-AMPK
TP53 Regulates Metabolic Genes
Neutrophil degranulation
Regulation of PTEN gene transcription
CDC42 GTPase cycle
RAC1 GTPase cycle
RAC2 GTPase cycle
RHOQ GTPase cycle
RHOH GTPase cycle
RHOG GTPase cycle
RHOJ GTPase cycle
RAC3 GTPase cycle
Amino acids regulate mTORC1
Eukaryotic Translation Elongation
Eukaryotic Translation Elongation
Peptide chain elongation
HSF1 activation
Neutrophil degranulation
Protein methylation
Chaperone Mediated Autophagy
Drugs
Zinc
Guanosine-5'-Diphosphate
Copper
Artenimol
Zinc acetate
Zinc chloride
Zinc sulfate, unspecified form
Diseases
GWAS
Interacting Genes
7 interacting genes:
ABCF3
CAPN1
CCDC90B
CTAG1A
CTAG1B
EEF1A1
TRIM14
135 interacting genes:
ABTB2
ACTB
ALPL
ANKRD24
ANXA7
APLP1
AQP2
ARIH2
AXIN1
BBS1
BBS2
BBS4
BRMS1
BTBD2
CASP2
CCL18
CDC25A
CDKN1A
CKS2
COX17
CRADD
CRCT1
CREBBP
CSRP2
DARS1
DIABLO
DLEU1
DNMT1
DUSP7
DYNLL1
DYSF
EIF3F
EP300
EXOSC4
FAS
GADD45A
GADD45G
HOXA1
HSPB2
HSPE1
HTRA2
IKBKG
IMMT
ITGB1BP1
ITSN1
KCNE3
KIF1B
LAMA4
LAMTOR1
LAMTOR5
LSM3
MAD2L1BP
MAGED2
MAP3K14
MAPK14
MLLT3
MNAT1
MRM1
MRPL42
MTRNR2L1
MYOC
NEU1
NRAS
NREP
OGT
ORMDL3
PABPC4
PAEP
PAFAH1B3
PAPSS1
PCDHA4
PFN2
PHYHIP
PKN2
PLAUR
PLCG1
POLE2
POLR2C
PQBP1
PRKCD
PSG9
PSMD11
PTPN4
PTPRCAP
PTPRF
RAB27A
RAP2A
RFC5
RGS12
RND1
RNF10
RPA2
RPLP1
RRAS
RSRC1
SARS2
SDHAF2
SERPINB5
SERPINB9
SFN
SHBG
SMAD2
SMAD4
SMN1
SNCA
SPP1
SSR1
STAT6
STMN2
SULT1E1
SUMO2
TAF9
TGIF1
TK1
TMPRSS3
TNFSF11
TP53BP2
TPT1
TRDMT1
TSC2
TSPY1
TSPYL2
TTLL12
TTR
TXNIP
UBQLN4
WARS1
XPO5
XRN2
YJU2B
YWHAG
ZBTB16
ZCCHC10
ZNF24
ZPR1
Entrez ID
55004
1915
HPRD ID
07933
00559
Ensembl ID
ENSG00000149357
ENSG00000156508
Uniprot IDs
Q6IAA8
P68104
Q6IPS9
PDB IDs
5X6U
5X6V
5Y39
5Y3A
6B9X
6EHP
6EHR
6NZD
6U62
6ULG
6WJ2
6WJ3
1SYW
3C5J
6ZMO
Enriched GO Terms of Interacting Partners
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