RHBDL2 and EFNB2

Number of citations of the paper that reports this interaction (PubMedID 15047175)
26

Data Source:
HPRD (in vitro)

		RHBDL2	EFNB2
Description		rhomboid like 2	ephrin B2
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane	Plasma Membrane Integral Component Of Plasma Membrane Adherens Junction Focal Adhesion Glutamatergic Synapse Integral Component Of Presynaptic Membrane
	Molecular Function	Serine-type Endopeptidase Activity	Virus Receptor Activity Protein Binding Ephrin Receptor Binding
	Biological Process	Proteolysis	Cell Migration Involved In Sprouting Angiogenesis Cell Adhesion Cell-cell Signaling Axon Guidance Positive Regulation Of Cell Population Proliferation Anatomical Structure Morphogenesis Negative Regulation Of Neuron Projection Development Viral Entry Into Host Cell Ephrin Receptor Signaling Pathway Blood Vessel Morphogenesis Regulation Of Chemotaxis Presynapse Assembly Positive Regulation Of Neuron Death Positive Regulation Of Cardiac Muscle Cell Differentiation
Pathways			EPH-Ephrin signaling EPH-Ephrin signaling EPHB-mediated forward signaling EPHB-mediated forward signaling Ephrin signaling Ephrin signaling EPH-ephrin mediated repulsion of cells
Drugs
Diseases
GWAS		Beard thickness ( 26926045) Blood protein levels ( 28240269) Menopause (age at onset) ( 22267201 26414677) Sweet beverage consumption ( 31046077) Triglyceride levels ( 32203549)	BMI x environmental factors (excluding physical activity) interaction ( 33654129) BMI x environmental factors (including physical activity) interaction ( 33654129) Left superior temporal gyrus thickness (schizophrenia interaction) ( 26249676) Metabolite levels ( 23823483) Pediatric autoimmune diseases ( 26301688) Subcutaneous adipose tissue ( 26480920)
Interacting Genes		5 interacting genes: EFNB2 EFNB3 MAP7D1 SLC35B4 TMBIM6	23 interacting genes: ANKRD46 DLG4 EPHA3 EPHA4 EPHB1 EPHB2 EPHB4 EPHB6 GRIP1 GRM1 GRM5 HOMER1 NCK2 PDZRN3 PECAM1 PICK1 PSEN1 PTPN13 RELN RGS3 RHBDL2 SDCBP SRC
Entrez ID		54933	1948
HPRD ID		07151	02754
Ensembl ID		ENSG00000158315	ENSG00000125266
Uniprot IDs		B7Z1Y9 Q9NX52	P52799
PDB IDs			2HLE 2I85 2VSK 2VSM 2WO2 3GXU 4UF7 6P7Y 6PDL
Enriched GO Terms of Interacting Partners?
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